LY86 and CD180

Number of citations of the paper that reports this interaction (PMID 9686597)
21

Data Source:
HPRD (in vivo, in vitro)

		LY86	CD180
Gene Name		lymphocyte antigen 86	CD180 molecule
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane	Plasma Membrane Integral Component Of Membrane
	Molecular Function
	Biological Process	Apoptotic Process Inflammatory Response Humoral Immune Response Cell Proliferation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response	B Cell Proliferation Involved In Immune Response Inflammatory Response Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Innate Immune System	Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Innate Immune System
Drugs
Diseases
GWAS		Major depressive disorder (broad) ( 20038947) Waist-hip ratio ( 23563607 20935629)	Prostate cancer (gene x gene interaction) ( 22219177)
Protein-Protein Interactions		2 interactors: APP CD180	1 interactors: LY86
Entrez ID		9450	4064
HPRD ID		05578	03749
Ensembl ID			ENSG00000134061
Uniprot IDs		O95711	Q99467
PDB IDs		3B2D	3B2D
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway B Cell Proliferation Involved In Immune Response Neuron Remodeling Cell Activation Innate Immune Response Cellular Copper Ion Homeostasis Regulation Of Lipopolysaccharide-mediated Signaling Pathway Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Immune Response Neuron Recognition RNA Polyadenylation Defense Response Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway B Cell Proliferation Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition B Cell Activation Involved In Immune Response Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Response To External Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning	Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Humoral Immune Response
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