CD180

Name	CD180 molecule
Structure
Novel Interactors	2 novel interactors: ADAMTS6 SELENOS
Interactors	1 interactors: LY86
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Plasma Membrane Membrane Mitotic Spindle
	Molecular Function	Lipopolysaccharide Immune Receptor Activity Protein Binding Signaling Receptor Activity
	Biological Process	B Cell Proliferation Involved In Immune Response Immune System Process Inflammatory Response Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway B Cell Proliferation Innate Immune Response Cellular Response To Lipopolysaccharide
Pathways	Toll Like Receptor 4 (TLR4) Cascade
GWAS	Common carotid intima-media thickness in HIV infection ( 29206233 ) General cognitive ability ( 29844566 ) Gut microbiota (bacterial taxa) ( 27723756 )
Entrez ID	4064
HPRD ID	03749
Ensembl ID	ENSG00000134061
Uniprot IDs	Q99467
PDB IDs	3B2D
GO Terms Enriched among Interactors ?	Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway ER Overload Response Very-low-density Lipoprotein Particle Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Negative Regulation Of Acute Inflammatory Response Negative Regulation Of D-glucose Transmembrane Transport Negative Regulation Of Glycogen Biosynthetic Process Low-density Lipoprotein Particle Regulation Of Acute Inflammatory Response To Antigenic Stimulus Ubiquitin-specific Protease Binding Derlin-1 Retrotranslocation Complex Negative Regulation Of Macrophage Apoptotic Process Negative Regulation Of D-glucose Import Negative Regulation Of Myeloid Cell Apoptotic Process Derlin-1-VIMP Complex Response To Redox State Regulation Of Lipopolysaccharide-mediated Signaling Pathway Aorta Development Coronary Vasculature Development Protein Exit From Endoplasmic Reticulum Regulation Of Myeloid Cell Apoptotic Process Antioxidant Activity Regulation Of Glycogen Biosynthetic Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Lipopolysaccharide-mediated Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway ER-nucleus Signaling Pathway Regulation Of Glycogen Metabolic Process Artery Development Cardiac Septum Development Cell Redox Homeostasis Regulation Of Acute Inflammatory Response Negative Regulation Of Interleukin-6 Production Negative Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Gluconeogenesis