NCR1 and TMEM50B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NCR1	TMEM50B
Description		natural cytotoxicity triggering receptor 1	transmembrane protein 50B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane SWI/SNF Complex	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune Response-regulating Signaling Pathway Cellular Defense Response Signal Transduction Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Cytotoxicity	Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)	Crohn's disease ( 23128233) Educational attainment ( 25201988)
Interacting Genes		8 interacting genes: ADAM33 APP CD247 CD59 FCER1G RHOU TMEM229B TMEM50B	21 interacting genes: AMIGO1 BCL2L1 CLRN1 CREB3L1 EDA FAM209A FXYD3 GPR152 GPX8 HLA-DPA1 LEPROTL1 LHFPL5 NCR1 SCN3B SLC10A6 SLC16A13 SLC35H1 TMEM14B TMEM52B TMEM88 TMX2
Entrez ID		9437	757
HPRD ID		05167	10747
Ensembl ID		ENSG00000189430	ENSG00000142188
Uniprot IDs		A0A0A0MQZ0 A0A0A0MR94 A0A0A0MTU0 O76036	F8WDH1 P56557 Q2V8N0
PDB IDs		1OLL 1P6F 6IAP
Enriched GO Terms of Interacting Partners?		Fc-gamma Receptor III Complex Myeloid Leukocyte Activation Plasma Membrane Protein Complex Positive Regulation Of Protein Localization To Cell Surface Leukocyte Activation Cell Activation Fc-gamma Receptor Signaling Pathway Regulation Of Protein Localization To Cell Surface Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding External Side Of Plasma Membrane Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Localization Fc Receptor Signaling Pathway Tertiary Granule Membrane IgE Receptor Activity Acetylcholine Receptor Activator Activity Positive Regulation Of Immune System Process PTB Domain Binding Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Membrane Regulation Of Immune Response Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6 Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Bacterium Endocytosis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Vesicle-mediated Transport Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Protein Localization Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Immune Effector Process Immune System Process Activation Of Immune Response Gamma-delta T Cell Receptor Complex Negative Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of Type I Hypersensitivity Negative Regulation Of Mast Cell Apoptotic Process Serotonin Secretion By Platelet	Membrane Mitochondrial Membrane
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