NCR1

Gene Name		natural cytotoxicity triggering receptor 1
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane SWI/SNF Complex
	Molecular Function	Receptor Signaling Protein Activity
	Biological Process	Cellular Defense Response Signal Transduction Natural Killer Cell Activation Intracellular Signal Transduction Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CD247 CD59 FCER1G
Entrez ID		9437
HPRD ID		05167
Ensembl ID		ENSG00000189430
Uniprot IDs		O76036
PDB IDs		1OLL 1P6F
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell Activation Regulation Of Cell Activation Regulation Of Acute Inflammatory Response Innate Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Type III Hypersensitivity Negative Regulation Of Activation Of Membrane Attack Complex Fc Receptor Mediated Stimulatory Signaling Pathway Immune Response Regulation Of Immune System Process Defense Response Positive Regulation Of T Cell Activation Positive Regulation Of Mast Cell Cytokine Production Positive Regulation Of Type I Hypersensitivity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Serotonin Secretion By Platelet Positive Regulation Of Type IIa Hypersensitivity Phagocytosis Fc Receptor Signaling Pathway Regulation Of Inflammatory Response Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Serotonin Secretion Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Immune System Process Positive Regulation Of Cell Adhesion Immune System Process Negative Regulation Of Mast Cell Apoptotic Process Regulation Of Lymphocyte Activation Regulation Of Mast Cell Apoptotic Process Serotonin Transport Positive Regulation Of Hypersensitivity Blood Coagulation Hemostasis Neutrophil Activation Involved In Immune Response Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Immune Response-regulating Signaling Pathway Positive Regulation Of Mast Cell Degranulation Positive Regulation Of Inflammatory Response To Antigenic Stimulus Negative Regulation Of Complement Activation Phagocytosis, Engulfment Positive Regulation Of Mast Cell Activation Regulation Of Body Fluid Levels Wound Healing Regulation Of Cell Adhesion Positive Regulation Of Immune Response Endocytosis
Tagcloud ?		adoptive antitumor capability chimeric combining effectors engineered fused genetically gtp immunotherapeutic killer meaningful mhc moieties ncrs nk nkp46 partly proto ral rala ralb recognition recognize regressions remarkable retrovirally termed