MAPK1IP1L and ARHGEF16

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAPK1IP1L	ARHGEF16
Gene Name		mitogen-activated protein kinase 1 interacting protein 1-like	Rho guanine nucleotide exchange factor (GEF) 16
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol
	Molecular Function		Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rho GTPase Binding PDZ Domain Binding Receptor Tyrosine Kinase Binding
	Biological Process		Small GTPase Mediated Signal Transduction Activation Of Rac GTPase Activity Activation Of Cdc42 GTPase Activity Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Cell Chemotaxis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Apoptotic Signaling Pathway
Pathways			Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS			Response to statin therapy ( 20339536)
Protein-Protein Interactions		15 interactors: ARHGEF16 C1orf94 CEP55 EWSR1 HGS HNRNPUL1 LENG8 PDCD6 RBFOX2 SS18L1 SUMO1 SUMO1P1 TFG UBE2I VPS37C	4 interactors: LNX1 MAPK1IP1L TFG YWHAQ
Entrez ID		93487	27237
HPRD ID		12647	12478
Ensembl ID		ENSG00000168175	ENSG00000130762
Uniprot IDs		Q8NDC0	B3KTS4 B4DJM7 Q5VV41
PDB IDs			1X6B
Enriched GO Terms of Interacting Partners?		Protein Sumoylation
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