VAMP3 and VAMP8

Number of citations of the paper that reports this interaction (PMID 12130530)
33

Data Source:
BioGRID (pull down)

		VAMP3	VAMP8
Gene Name		vesicle-associated membrane protein 3	vesicle-associated membrane protein 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Integral Component Of Membrane Apical Plasma Membrane Cell Junction Clathrin-coated Vesicle Secretory Granule Clathrin-coated Vesicle Membrane SNARE Complex Neuron Projection Intracellular Membrane-bounded Organelle Recycling Endosome	Cytoplasm Mitochondrion Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Cell Surface Membrane Integral Component Of Membrane Secretory Granule Membrane SNARE Complex Late Endosome Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Vesicular Exosome Mucin Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin-1 Binding	SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Positive Regulation Of Receptor Recycling Protein Complex Assembly Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Neurotransmitter Secretion Vesicle-mediated Transport Calcium Ion-dependent Exocytosis Substrate Adhesion-dependent Cell Spreading SNARE Complex Assembly Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Immunoglobulin Secretion Membrane Fusion Mucus Secretion Negative Regulation Of Secretion By Cell Regulation Of Histamine Secretion By Mast Cell	Autophagic Vacuole Fusion Exocytosis Post-Golgi Vesicle-mediated Transport Endocytosis Vesicle Fusion Protein Transport Regulation Of Endocytosis SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Periodontal microbiota ( 22699663)	Prostate cancer ( 21743467)
Protein-Protein Interactions		14 interactors: ACAP1 APP BCAP31 BCL2L13 DDB1 IKBKG NELFE SNAP23 STX16 STX2 STX3 STX4 VAMP2 VAMP8	12 interactors: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3
Entrez ID		9341	8673
HPRD ID		04711	04415
Ensembl ID		ENSG00000049245	ENSG00000118640
Uniprot IDs		Q15836 Q6FGG2 Q9BRV4	Q9BV40
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Organelle Fusion Membrane Fusion Vesicle Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Vesicle Exocytosis Exocytosis Establishment Of Vesicle Localization Vesicle Localization Neurotransmitter Secretion Synaptic Vesicle Transport Golgi Vesicle Transport Secretion By Cell Establishment Of Localization In Cell Regulation Of Neurotransmitter Levels Protein Transport Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Protein Localization Intracellular Transport Secretion Neurotransmitter Transport Cellular Localization Organelle Localization Vesicle Docking Post-Golgi Vesicle-mediated Transport Protein Localization Membrane Organization Membrane Docking Long-term Synaptic Potentiation Regulation Of Protein Localization To Plasma Membrane Intracellular Protein Transport Positive Regulation Of Protein Localization To Cell Surface SNARE Complex Assembly Synaptic Transmission Positive Regulation Of Synaptic Transmission Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Cellular Protein Localization Transport Positive Regulation Of Peptidase Activity Response To Hydroperoxide Regulation Of Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Signaling Regulation Of Synaptic Plasticity Cell-cell Signaling Organelle Organization Positive Regulation Of Catalytic Activity Endoplasmic Reticulum Calcium Ion Homeostasis	Vesicle Fusion Membrane Fusion Organelle Fusion Synaptic Vesicle Fusion To Presynaptic Membrane Vesicle Organization Neurotransmitter Secretion Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Neurotransmitter Transport Vesicle Docking Membrane Docking Organelle Localization Synaptic Vesicle Transport Membrane Organization Establishment Of Organelle Localization Exocytosis Establishment Of Vesicle Localization Vesicle Localization Post-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Secretion By Cell Positive Regulation Of Synaptic Transmission Cell-cell Signaling Vesicle-mediated Transport Regulation Of Synaptic Transmission Synaptic Transmission Regulation Of Cellular Localization Cellular Localization Secretion Long-term Synaptic Potentiation Protein Transport Intracellular Protein Transport Establishment Of Protein Localization Organelle Organization Intracellular Transport Golgi Vesicle Transport Glutamate Secretion Regulation Of Secretion Cellular Protein Complex Assembly Protein Localization Regulation Of Exocytosis Regulation Of Protein Localization Regulation Of Synaptic Plasticity Cellular Protein Localization Calcium Ion-dependent Exocytosis Regulation Of Protein Localization To Plasma Membrane Regulation Of Insulin Secretion Regulation Of Synaptic Vesicle Priming Regulation Of Peptide Hormone Secretion Acid Secretion
Tagcloud ?		cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 glut4 immunoprecipitation insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia vamp2 vesicle vesicles	3t3 adipocytes characterised complexes consists facet finding fulfil glut4 immunoprecipitation isoforms l1 others propose sds snap23 snare subcellular syntaxin4 systematic trafficking vamp2 vamp3 vamps vary vesicle vesicles
Tagcloud (Difference) ?		cellubrevin coimmunoprecipitation consistent cytoplasmic deleted domains glut1 insulin introduction membrane microinjection neither plasma recombinant requirement responsive resulted site snap stimulated syntaxin translocation vaccinia	3t3 adipocytes characterised complexes consists facet finding fulfil isoforms l1 others propose sds snap23 snare subcellular syntaxin4 systematic trafficking vamps vary
Tagcloud (Intersection) ?		glut4 immunoprecipitation vamp2 vamp3 vesicle vesicles