TMEM60 and SLC30A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM60	SLC30A2
Description		transmembrane protein 60	solute carrier family 30 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Mitochondrion Mitochondrial Inner Membrane Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Endosome Membrane Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Zymogen Granule Membrane Secretory Vesicle
	Molecular Function	Protein Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Identical Protein Binding Metal Ion Binding Zinc:proton Antiporter Activity
	Biological Process		Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Response To Zinc Ion Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Export Across Plasma Membrane Zinc Ion Import Into Secretory Vesicle Zinc Ion Import Into Zymogen Granule Zinc Ion Import Into Lysosome Zinc Ion Import Into Mitochondrion
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 30604766 31152163 31451708) Estimated glomerular filtration rate in non-diabetics ( 31451708) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199)
Interacting Genes		91 interacting genes: AMIGO1 ANKS6 APOL2 AQP2 AQP6 ARL13B ASGR2 BEST2 BIK BSND CD300A CD53 CD74 CLDN7 CNR2 CPLX4 CYB5R3 EBP EDA ERGIC3 EVI2B FAM209A FFAR2 FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPR42 GPX8 HERPUD2 HIBADH HSD17B13 IFNGR2 KCNK5 KIAA2013 LEUTX LHFPL5 LMNA LRRC3B LRRC59 MFF MGST3 MMD MMGT1 PAGE1 PGRMC2 PI16 REEP2 REEP4 RETREG3 RHCG RNASEK SCN3B SLC10A1 SLC10A6 SLC13A4 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC30A4 SLC35E3 SLC35H1 SLC38A1 SLC39A2 SLC4A1 SLC7A8 SPAG4 SPNS3 SSMEM1 STOM STX1A SYT1 THAP4 TLCD4 TMCO5A TMED9 TMEM139 TMEM14B TMEM203 TMEM237 TMEM45B TMEM52B TMEM86B TMEM9 TMPPE TMPRSS2 TTYH1 VMA21	67 interacting genes: ABHD16A ADAM33 AQP2 AQP6 ATP13A1 C5orf46 CCL4 CCL4L2 CD40 CD52 CD79A CD99L2 CPLX4 CREB3 CTSA CYB561D2 EBAG9 EMP3 ERGIC3 EVI2B F11R FAM174A FDPS FFAR2 FXYD3 FXYD6 GALNT15 GJA5 GJB2 GJB5 GLB1 GOLT1A GPR161 GPR42 GPRC5D HGFAC KASH5 KCNN4 LMNA LTA LYVE1 MS4A13 NDUFAF1 NRM OPRM1 PCNX2 PLPPR1 PVR SEC22A SELL SERPING1 SLC10A6 SLC16A2 SLC18A1 SLC38A7 SLC39A2 SLC7A1 SLC7A8 TAS2R5 TM4SF18 TMEM107 TMEM52B TMEM60 TMEM86A TNFRSF12A TRARG1 YIPF2
Entrez ID		85025	7780
HPRD ID		12923	18057
Ensembl ID		ENSG00000135211	ENSG00000158014
Uniprot IDs		Q9H2L4	Q9BRI3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Protein Binding Monoatomic Ion Transport Plasma Membrane Basolateral Plasma Membrane Inorganic Ion Transmembrane Transport Monoatomic Cation Transport Endoplasmic Reticulum Membrane Transport Vesicle Membrane Monoatomic Ion Transmembrane Transport Endoplasmic Reticulum Antiporter Activity Metal Ion Transport Organic Anion Transport Inorganic Cation Transmembrane Transport Inorganic Anion Transmembrane Transport Cytoplasmic Vesicle Zinc Export Across Plasma Membrane Inorganic Anion Transport Monoatomic Cation Transmembrane Transport Connexin Complex Chloride Transmembrane Transport Gap Junction Channel Activity Regulation Of PH Symporter Activity Neurotransmitter Transport Zinc Ion Import Into Lysosome Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Carbon Dioxide Transmembrane Transporter Activity Chloride Transport Carbon Dioxide Transmembrane Transport Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Zinc Ion Transmembrane Transporter Activity Lysosomal Lumen Acidification Gap Junction Zinc Ion Transmembrane Transport Transmembrane Transporter Activity Zinc Ion Transport Gap Junction-mediated Intercellular Transport Sodium Ion Transport Carboxylic Acid Transmembrane Transport Organic Acid Transmembrane Transport Carboxylic Acid Transport Organic Acid Transport Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Proton-transporting V-type ATPase Complex Assembly	Membrane Transmembrane Transport Plasma Membrane Connexin Complex Gap Junction Channel Activity Gap Junction Renal Water Transport Gap Junction Assembly Positive Regulation Of Sodium Ion Export Across Plasma Membrane Ion Channel Regulator Activity CCR1 Chemokine Receptor Binding Amino Acid Import Across Plasma Membrane Amino Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transport Thyroid Hormone Transmembrane Transporter Activity Metal Ion Transport Protein Binding Positive Regulation Of Immune System Process Monoatomic Cation Transport Aromatic Amino Acid Transport
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