GTF3C3 and DEDD2

Number of citations of the paper that reports this interaction (PMID 11965497)
8

Data Source:
BioGRID (pull down)
HPRD (in vitro, two hybrid, in vivo)

		GTF3C3	DEDD2
Gene Name		general transcription factor IIIC, polypeptide 3, 102kDa	death effector domain containing 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding Receptor Signaling Complex Scaffold Activity
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Transcription, DNA-templated RNA Processing Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors RRNA Catabolic Process Cellular Homeostasis Apoptotic Nuclear Changes Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BRF1 DEDD DEDD2 GTF3C5 HNRNPD PCBD1 TBP	11 interactors: CASP10 CASP8 CDCA7L CDK6 CFLAR DEDD GTF3C3 HNRNPAB NR2E3 RBFOX2 RHOXF2
Entrez ID		9330	162989
HPRD ID		11997	10868
Ensembl ID		ENSG00000119041	ENSG00000160570
Uniprot IDs		Q9Y5Q9	Q8WXF8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase III Promoter RNA Metabolic Process TRNA Transcription Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Aromatic Compound Catabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Catabolic Process Biosynthetic Process RRNA Transcription Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Extrinsic Apoptotic Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Proepicardium Development Catabolic Process Placenta Development Cellular Macromolecule Catabolic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Circadian Regulation Of Translation DNA-templated Transcription, Initiation Apoptotic Process Programmed Cell Death Transcription Initiation From RNA Polymerase III Promoter Cell Death Death Tetrahydrobiopterin Biosynthetic Process Cellular Metabolic Process Regulation Of Translation Negative Regulation Of Transcription, DNA-templated Chorio-allantoic Fusion Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RRNA Catabolic Process L-phenylalanine Catabolic Process	Regulation Of Necroptotic Process Regulation Of Necrotic Cell Death Tissue Development Regulation Of Myeloid Cell Differentiation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Organ Development Regulation Of Erythrocyte Differentiation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Regulation Of Cell Proliferation Apoptotic Signaling Pathway Cell Dedifferentiation Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Development Programmed Cell Death Activation Of Cysteine-type Endopeptidase Activity System Development Regulation Of Metabolic Process Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Cell Death Death Extrinsic Apoptotic Signaling Pathway Regulation Of Transcription, DNA-templated Zymogen Activation Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Rhodopsin Gene Expression Negative Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Endopeptidase Activity Regulation Of Rhodopsin Gene Expression Negative Regulation Of Myoblast Fusion Multicellular Organismal Development Positive Regulation Of Peptidase Activity Cell Differentiation Negative Regulation Of Gene Expression Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Anatomical Structure Development Negative Regulation Of Biosynthetic Process
Tagcloud ?			annotation atra bindings birc3 braf casp4 casp8 changed effector erk expressions fas fate fenretinide fewer hspa1a huh7 inducing mek participated profiled raf ras rxralpha sosc2 tnfaip3 tnfalpha traf2 uses
Tagcloud (Difference) ?			annotation atra bindings birc3 braf casp4 casp8 changed effector erk expressions fas fate fenretinide fewer hspa1a huh7 inducing mek participated profiled raf ras rxralpha sosc2 tnfaip3 tnfalpha traf2 uses
Tagcloud (Intersection) ?