TRIP10 and ARHGAP44

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TRIP10	ARHGAP44
Gene Name		thyroid hormone receptor interactor 10	Rho GTPase activating protein 44
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Cytosol Cell Junction Leading Edge Membrane Dendritic Spine Synapse Recycling Endosome
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process	Endocytosis Cell Communication Signal Transduction Small GTPase Mediated Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction	Exocytosis Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ABL2 AKAP9 ARHGAP12 ARHGAP17 ARHGAP44 CDC42 CREBBP CTNNB1 DNM2 HTT LYN PDE6G POT1 PRKACA RHOJ RHOQ RXRA SH3BP1 SMARCE1 SRC STAT3 TERF1 THRB TINF2 WAS WASF1 WASL WBP11	4 interactors: CDC42 HN1 RAC1 TRIP10
Entrez ID		9322	9912
HPRD ID		05142	13810
Ensembl ID		ENSG00000125733	ENSG00000006740
Uniprot IDs		Q15642	A6NCP5 E7ERK8 Q17R89 Q69Z00
PDB IDs		2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Signal Transduction Regulation Of Catalytic Activity Signaling Cell Communication Regulation Of Cellular Component Organization Positive Regulation Of Cellular Metabolic Process Regulation Of Organelle Organization Cellular Response To Stimulus Cellular Component Assembly Organelle Organization Anatomical Structure Morphogenesis Positive Regulation Of Organelle Organization Regulation Of Intracellular Signal Transduction Negative Regulation Of Telomere Maintenance Via Telomerase Response To Stimulus Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Organonitrogen Compound Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Actin Nucleation Regulation Of Signal Transduction Regulation Of Cytoskeleton Organization Regulation Of Cellular Process Negative Regulation Of Telomere Maintenance Negative Regulation Of Biosynthetic Process Homeostatic Process Epithelium Development Innate Immune Response Cellular Response To Hormone Stimulus Regulation Of Telomere Maintenance Via Telomerase Cellular Response To Organic Cyclic Compound Actin Cytoskeleton Organization Cytoskeleton Organization Regulation Of Signaling Cell Development Small GTPase Mediated Signal Transduction Movement Of Cell Or Subcellular Component Response To Organic Cyclic Compound Actin Filament-based Process Phagocytosis Developmental Process Positive Regulation Of Catalytic Activity Anatomical Structure Development Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Hormone Positive Regulation Of Cellular Biosynthetic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Fc-gamma Receptor Signaling Pathway	Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Lipid Kinase Activity Positive Regulation Of DNA Replication T Cell Costimulation Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Actin Filament-based Process Endocytosis Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Projection Assembly Positive Regulation Of Cell-substrate Adhesion Regulation Of DNA Replication Epidermal Cell Differentiation Positive Regulation Of DNA Metabolic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell-substrate Adhesion Cytoskeleton Organization Epithelial Cell Development Positive Regulation Of T Cell Activation Cell-cell Junction Organization Actin Filament Branching Engulfment Of Apoptotic Cell Submandibular Salivary Gland Formation Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Mast Cell Chemotaxis Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Cell-cell Adhesion Phagocytosis Epidermis Development Fc Receptor Signaling Pathway Wnt Signaling Pathway Positive Regulation Of Cell Projection Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Cell Projection Assembly Regulation Of T Cell Activation Regulation Of Lipid Metabolic Process
Tagcloud ?		10q21 5q31 5qnca arphpv assembling bipartite c2hc4 c5orf7 d10s1225 dkfzp761f0118 egr2 fbh fch flj14374 fnbp1 informatics jmjc l40411 ncrna overlapped paralogous syndromic tri8h1 tri8h2 trip8 tsga
Tagcloud (Difference) ?		10q21 5q31 5qnca arphpv assembling bipartite c2hc4 c5orf7 d10s1225 dkfzp761f0118 egr2 fbh fch flj14374 fnbp1 informatics jmjc l40411 ncrna overlapped paralogous syndromic tri8h1 tri8h2 trip8 tsga
Tagcloud (Intersection) ?