MS4A1 and CSNK2A2

Number of citations of the paper that reports this interaction (PMID 7678037)
2

Data Source:
HPRD (in vitro)

		MS4A1	CSNK2A2
Gene Name		membrane-spanning 4-domains, subfamily A, member 1	casein kinase 2, alpha prime polypeptide
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane External Side Of Plasma Membrane Extracellular Vesicular Exosome	Nucleus Cytosol PcG Protein Complex
	Molecular Function	Epidermal Growth Factor Receptor Binding MHC Class II Protein Complex Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein N-terminus Binding
	Biological Process	Humoral Immune Response B Cell Proliferation	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Axon Guidance Wnt Signaling Pathway Mitotic Spindle Checkpoint
Pathways			Mitotic Prometaphase Signal transduction by L1 Axon guidance misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling L1CAM interactions Signaling by Wnt Cell Cycle, Mitotic M Phase WNT mediated activation of DVL TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by WNT in cancer Condensation of Prometaphase Chromosomes
Drugs		Rituximab Ibritumomab Tositumomab
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CCDC155 CD40 CSNK2A1 CSNK2A2 FYN LCK LYN MDM2	92 interactors: ABCA1 ACACA ADH1A AQP4 ARR3 ARRB2 ASL ATF1 ATF2 BID CABP1 CALM1 CASQ2 CAV1 CDC37 CLTB CREBBP CREM CSN3 CSNK2B CTDP1 DCPS EEF1B2 EIF2B2 EIF2B5 EIF4EBP1 ERH FGF1 FGF2 FKBP3 FOS GTF2A1 GTF2A1L HDAC1 HDAC2 HDAC6 HIST1H1C HMGA1 HMGA2 HNRNPC HSP90AA1 HSP90B1 HSPH1 IL16 JUN KIF1C KLF1 LAMC3 LGALS3 MAF1 MAPK14 MGMT MS4A1 MYC MYCN MYF5 NAP1L4 NCL P4HB PAK1 PIN1 PIN4 PPP1R1B PPP1R2 PPP1R8 PRNP PTEN PTPN1 PTPRC RELA RGS19 SAT1 SLC18A2 SMURF1 SNCA SNX6 SPIB SPP1 STX1A TCF7L2 TCOF1 TGFBR1 TGM2 TOP1 TRIM41 TTLL12 UBE2R2 WAS XRCC1 ZNF219 ZNF670 ZNHIT3
Entrez ID		931	1459
HPRD ID		00204	00279
Ensembl ID		ENSG00000156738	ENSG00000070770
Uniprot IDs		B4DT24 P11836	P19784
PDB IDs		1S8B 2OSL 3BKY 3PP4	3E3B 3OFM 3U87
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To External Stimulus Immune Response-regulating Signaling Pathway Peptidyl-tyrosine Autophosphorylation Platelet Activation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Regulation Of Protein Metabolic Process Fc-epsilon Receptor Signaling Pathway Positive Regulation Of JAK-STAT Cascade Fc Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Proliferation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus T Cell Costimulation Regulation Of Cell Death Cellular Response To Peptide Regulation Of JAK-STAT Cascade Regulation Of Immune Response Negative Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Axon Guidance Regulation Of Lymphocyte Activation Cell Surface Receptor Signaling Pathway Negative Regulation Of Protein Catabolic Process Blood Coagulation Hemostasis Regulation Of Cellular Protein Metabolic Process Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Abiotic Stimulus Regulation Of Cell Activation Antigen Receptor-mediated Signaling Pathway Phosphatidylinositol-mediated Signaling Response To Peptide Leukocyte Activation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Response To Drug Positive Regulation Of Peptidyl-tyrosine Phosphorylation Axonogenesis Mitotic Cell Cycle Checkpoint Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Viral Process Positive Regulation Of Protein Metabolic Process Locomotion Positive Regulation Of Signal Transduction Axon Development	Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Stress Response To Abiotic Stimulus Response To Organonitrogen Compound Positive Regulation Of Metabolic Process Cellular Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Stimulus Regulation Of Gene Expression Developmental Process Innate Immune Response Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Immune System Process Response To Growth Factor Enzyme Linked Receptor Protein Signaling Pathway Tissue Development Regulation Of Signal Transduction Regulation Of Nitrogen Compound Metabolic Process Response To Stimulus Immune Response-regulating Signaling Pathway Cellular Response To Stress Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulation Of Cellular Protein Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Immune Response Response To Organic Cyclic Compound Regulation Of Signaling Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process Gene Expression Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process RNA Biosynthetic Process Immune Response Regulation Of Phosphorylation Cell Differentiation Negative Regulation Of Signal Transduction Anatomical Structure Development Nitrogen Compound Metabolic Process Multicellular Organismal Development Defense Response Macromolecule Biosynthetic Process Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression
Tagcloud ?		bbc3 bllf1 brlf1 cdh17 chga cldn18 eber1 eber2 fcer2 fcgr2b fcrl3 fscn1 gast housekeeper ifitm1 inhba lymphoepithelioma macrodissected nanostring ncounter olfm4 plunc reg4 sdc1 serpinh1 slc2a1 sulf1 tnfsf9 tyms	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
Tagcloud (Difference) ?		bbc3 bllf1 brlf1 cdh17 chga cldn18 eber1 eber2 fcer2 fcgr2b fcrl3 fscn1 gast housekeeper ifitm1 inhba lymphoepithelioma macrodissected nanostring ncounter olfm4 plunc reg4 sdc1 serpinh1 slc2a1 sulf1 tnfsf9 tyms	bovine casein catalytic cattle chromosome chromosomes coast composed conserved defined east encoding fever genomes homology hybrid mapped panel parasitic polymerase rodent segment somatic subunit subunits synteny theileriosis
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