ZBTB47 and CBFA2T3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB47	CBFA2T3
Description		zinc finger and BTB domain containing 47	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Nucleus Nucleoplasm Nucleolus Golgi Apparatus Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Response To Hypoxia DNA-templated Transcription Negative Regulation Of Cell Population Proliferation Cell Differentiation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of DNA-templated Transcription Regulation Of Aerobic Respiration
Pathways
Drugs
Diseases
GWAS			Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		14 interacting genes: CBFA2T3 CCDC136 CEP70 DSCAM DVL3 HOOK1 HOOK2 MTUS2 NCKIPSD PNMA3 TLE5 ZNF16 ZNF394 ZRANB1	23 interacting genes: ARHGEF6 CBFA2T2 CHRM4 DRC4 EPM2AIP1 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652
Entrez ID		92999	863
HPRD ID		15888	04847
Ensembl ID		ENSG00000114853	ENSG00000129993
Uniprot IDs		A0A7P0T820 Q9UFB7	O75081
PDB IDs			9DE2
Enriched GO Terms of Interacting Partners?		FHF Complex Protein Localization To Perinuclear Region Of Cytoplasm HOPS Complex Early Endosome To Late Endosome Transport Dynein Light Intermediate Chain Binding Vacuole Organization Wnt Signaling Pathway Cellular Response To Sodium Dodecyl Sulfate Microtubule Binding Lysosome Organization Cytoplasmic Microtubule Organization Endosome To Lysosome Transport Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Centrosome Vesicle Organization Endosome Organization	Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Biosynthetic Process Protein Lysine Delactylase Activity Methyl-CpG Binding Negative Regulation Of RNA Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Transcription Corepressor Binding DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Histone Deacetylase Activity, Hydrolytic Mechanism Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Zinc Ion Binding Protein Deacetylation Protein Lysine Deacetylase Activity Transcription Corepressor Activity Nucleoplasm NuRD Complex RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Myotube Differentiation Negative Regulation Of Macromolecule Metabolic Process Histone Deacetylase Activity Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Cell Fate Specification Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Macromolecule Deacylation NF-kappaB Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Telomere Tethering At Nuclear Periphery Cis-trans Isomerase Activity Positive Regulation Of Ferroptosis Methyl-CpNpG Binding Regulation Of Metabolic Process Negative Regulation Of Striated Muscle Cell Differentiation Histone Deacetylase Complex Regulation Of Myotube Differentiation Regulation Of Cell Fate Commitment
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