TMEM14C and TMEM35A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM14C	TMEM35A
Description		transmembrane protein 14C	transmembrane protein 35A
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Transmembrane Transporter Activity	Protein Binding Acetylcholine Receptor Regulator Activity
	Biological Process	Heme Biosynthetic Process Mitochondrial Transport Erythrocyte Differentiation Transmembrane Transport Regulation Of Heme Biosynthetic Process	Chaperone-mediated Protein Complex Assembly Positive Regulation Of Protein Localization To Cell Surface
Pathways
Drugs
Diseases
GWAS		Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
Interacting Genes		51 interacting genes: AQP6 ARL13B BCL2L13 BIK CLDN5 COMT COQ9 CPLANE2 CREB3 CREB3L1 CYB5R3 EBP ELOVL7 FAM209A GJB1 GORAB GPR152 GPX8 HSD17B13 KASH5 LMNA LNX1 MARCHF8 MFF MMGT1 MTERF3 MUC1 NCAPH2 NCR3LG1 PDZK1IP1 PLIN3 RCHY1 SAR1A SDC3 SHANK3 SLC10A6 SLC18A1 SLC35H1 SSMEM1 STX1A SYT1 TMEM14B TMEM31 TMEM35A TMEM52B TMEM79 TMEM86B TMX2 VSIR ZDHHC15 ZFYVE27	32 interacting genes: ADIPOQ APP BET1 C16orf92 CMTM5 COX20 CTSA CXCL16 CYB5B EHHADH FXYD6 GIMAP1 GOSR2 LNPEP MGLL ORMDL1 RTP2 RUSF1 THBD TMEM106C TMEM120A TMEM14C TMEM201 TMEM222 TMEM229B TMEM243 TMEM42 TRIM55 TRIM63 VAMP1 VAMP3 VAPA
Entrez ID		51522	59353
HPRD ID		15524	06523
Ensembl ID		ENSG00000111843	ENSG00000126950
Uniprot IDs		Q9P0S9	Q53FP2
PDB IDs		2LOS	9H9E
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Identical Protein Binding Protein Binding Mitochondrial Membrane Endoplasmic Reticulum Clathrin-sculpted Monoamine Transport Vesicle Membrane Organelle Organization Norepinephrine Transport	Membrane Membrane Fusion SNAP Receptor Activity SNARE Complex Vesicle Fusion Organelle Membrane Fusion Organelle Fusion Membrane Organization Sphingomyelin Biosynthetic Process SNARE Complex Assembly Cellular Localization Endoplasmic Reticulum Vesicle Organization Positive Regulation Of CAMP/PKA Signal Transduction Response To CAMP Endoplasmic Reticulum Membrane Sphingomyelin Metabolic Process
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