NLGN4X and DLGAP2

Number of citations of the paper that reports this interaction (PubMedID 11368788)
23

Data Source:
HPRD (in vitro)

		NLGN4X	DLGAP2
Description		neuroligin 4 X-linked	DLG associated protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Dendrite Synapse Postsynaptic Membrane Excitatory Synapse Postsynaptic Density Membrane Glutamatergic Synapse GABA-ergic Synapse Symmetric, GABA-ergic, Inhibitory Synapse Neuron To Neuron Synapse Asymmetric, Glutamatergic, Excitatory Synapse Postsynaptic Specialization Membrane	Neurofilament Plasma Membrane Postsynaptic Density Membrane Synapse Glutamatergic Synapse Postsynaptic Specialization
	Molecular Function	Protein Binding Chloride Ion Binding Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding	Protein Binding Molecular Adaptor Activity
	Biological Process	Brainstem Development Cell Adhesion Neuron Cell-cell Adhesion Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Modulation Of Chemical Synaptic Transmission Synapse Organization Regulation Of Synapse Assembly Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Presynapse Assembly	Neuron-neuron Synaptic Transmission Signaling Modulation Of Chemical Synaptic Transmission
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)	Bipolar disorder ( 31043756) Daytime nap ( 33568662) End-stage renal disease ( 29885931) Eye morphology ( 29921221) Femur bone mineral density x serum urate levels interaction ( 34046847) Lung cancer ( 28604730) Menarche (age at onset) ( 23599027) Neuritic plaque ( 31497858) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive astigmatism ( 30306274) Stroke ( 32693751) Tau burden ( 33426524) Triglycerides ( 24886709) White matter microstructure in first episode schizophrenia (right posterior cingulate cortex) ( 28924203)
Interacting Genes		2 interacting genes: DLG4 DLGAP2	18 interacting genes: ABI2 ADRB1 CYSRT1 DGCR6 DLG2 DLG4 DLGAP1 GRK5 KRT40 KRTAP4-2 MAGI2 NLGN4X NOS1 SHANK2 SHANK3 SORBS2 TSPOAP1 UBASH3B
Entrez ID		57502	9228
HPRD ID		02336	09258
Ensembl ID		ENSG00000146938	ENSG00000198010
Uniprot IDs		A8K4S1 B3KP11 Q8N0W4	A0A1B0GTN4
PDB IDs		2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?			Postsynaptic Density Vocalization Behavior Ionotropic Glutamate Receptor Binding Receptor Clustering Synapse Social Behavior Dendritic Spine Scaffold Protein Binding Beta-1 Adrenergic Receptor Binding Synaptic Receptor Adaptor Activity AMPA Glutamate Receptor Clustering Modulation Of Chemical Synaptic Transmission Modulation Of Excitatory Postsynaptic Potential Learning Neuron Projection Cell Projection Synaptic Signaling Neuron Spine Photoreceptor Inner Segment Juxtaparanode Region Of Axon Regulation Of Membrane Potential Neurotransmitter-gated Ion Channel Clustering Cellular Response To Potassium Ion Postsynaptic Membrane Dendritic Spine Morphogenesis Kinase Binding Postsynaptic Density Membrane Learning Or Memory Calyx Of Held Response To Potassium Ion SH3 Domain Binding Cytoskeletal Anchor Activity Regulation Of System Process Regulation Of Nervous System Process Regulation Of Cell Communication Regulation Of Signaling Protein Localization To Membrane Chemical Synaptic Transmission Cognition Regulation Of The Force Of Heart Contraction Regulation Of Long-term Neuronal Synaptic Plasticity Cell-cell Signaling Trans-synaptic Signaling Signaling Excitatory Synapse Positive Regulation Of Synaptic Transmission Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Adult Behavior Cell Communication
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?