NLGN4X

Gene Name		neuroligin 4, X-linked
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Postsynaptic Density Integral Component Of Membrane Cell Junction Dendrite Synapse Postsynaptic Membrane Excitatory Synapse
	Molecular Function	Receptor Activity Protein Binding Chloride Ion Binding Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Brainstem Development Neuron Cell-cell Adhesion Learning Metabolic Process Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Regulation Of Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Membrane Potential Presynaptic Membrane Assembly
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: DLG4 DLGAP2
Entrez ID		57502
HPRD ID		02336
Ensembl ID		ENSG00000146938
Uniprot IDs		A8K4S1 B3KP11 Q8N0W4
PDB IDs		2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?		Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Maintenance Of Apical/basal Cell Polarity Receptor Localization To Synapse Synaptic Transmission Negative Regulation Of Receptor Internalization Locomotory Exploration Behavior Dendritic Spine Morphogenesis Maintenance Of Cell Polarity Synaptic Vesicle Maturation Vocalization Behavior Dendritic Spine Development Protein Localization To Synapse Cell-cell Signaling Negative Regulation Of Receptor-mediated Endocytosis Dendritic Spine Organization Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Cortical Actin Cytoskeleton Organization Exploration Behavior Postsynaptic Membrane Organization Establishment Or Maintenance Of Apical/basal Cell Polarity Cortical Cytoskeleton Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Receptor Internalization Positive Regulation Of Excitatory Postsynaptic Membrane Potential Golgi To Plasma Membrane Transport Synaptic Vesicle Endocytosis Synaptic Vesicle Recycling Social Behavior Positive Regulation Of Membrane Potential Negative Regulation Of Endocytosis Receptor Clustering Regulation Of Neuronal Synaptic Plasticity Nucleotide Phosphorylation Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Neuromuscular Process Controlling Balance Synapse Assembly Dendrite Morphogenesis Post-Golgi Vesicle-mediated Transport Synaptic Vesicle Transport Positive Regulation Of Synaptic Transmission Membrane Depolarization Regulation Of Receptor Activity Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Neuromuscular Process Learning
Tagcloud ?		agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 ostn rorb shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2