CHMP7 and PAFAH1B3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CHMP7	PAFAH1B3
Description		charged multivesicular body protein 7	platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore Chromatin ESCRT III Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Lysosomal Membrane Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Multivesicular Body Membrane Amphisome Membrane	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane
	Molecular Function	Protein Binding	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Exit From Mitosis Protein Transport Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Protein Localization To Chromatin Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly	Lipid Metabolic Process Spermatogenesis Nervous System Development Lipid Catabolic Process
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex	COPI-independent Golgi-to-ER retrograde traffic
Drugs			(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732625) Brain morphology (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: CREB3 OGT PAFAH1B3 TRIM55 TRIM63 USP8	37 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		91782	5050
HPRD ID		14534	04354
Ensembl ID		ENSG00000147457	ENSG00000079462
Uniprot IDs		B3KMN6 B3KRZ9 B3KUH0 Q8WUX9	A0A024R0L6 Q15102
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Negative Regulation Of Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Deacetylase Activity Platelet-activating Factor Acetyltransferase Activity 1-alkyl-2-acetylglycerophosphocholine Esterase Activity 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Intracellular Signal Transduction Regulation Of Generation Of Precursor Metabolites And Energy Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Response To Hormone Post-translational Protein Modification Negative Regulation Of Lysosomal Protein Catabolic Process Intracellular Signaling Cassette Response To Glucocorticoid Response To Corticosteroid Response To Steroid Hormone Positive Regulation Of Amyloid Fibril Formation Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission CCR1 Chemokine Receptor Binding Release From Viral Latency Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Regulation Of Transcription By Glucose Muscle Atrophy CAMP Response Element Binding Protein Binding NSL Complex Regulation Of Lysosomal Protein Catabolic Process Signal Transduction Titin Binding Contractile Muscle Fiber Cytoplasm Regulation Of Small Molecule Metabolic Process Induction Of Positive Chemotaxis Microtubule K63-linked Deubiquitinase Activity	Nuclear Telomere Cap Complex Identical Protein Binding 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Telomeric DNA Binding Protein Heterodimerization Activity Negative Regulation Of Telomere Maintenance Shelterin Complex Nucleolus Double-stranded Telomeric DNA Binding G-rich Strand Telomeric DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Capping
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