CHMP7

Description		charged multivesicular body protein 7
Image		No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Kinetochore Chromatin ESCRT III Complex Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Lysosomal Membrane Multivesicular Body Kinetochore Microtubule Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Midbody Multivesicular Body Membrane Amphisome Membrane
	Molecular Function	Protein Binding
	Biological Process	Plasma Membrane Repair Vesicle Budding From Membrane Autophagy Nucleus Organization Vacuolar Transport Mitotic Metaphase Chromosome Alignment Exit From Mitosis Protein Transport Nuclear Membrane Reassembly Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Viral Budding From Plasma Membrane Vesicle Fusion With Vacuole Multivesicular Body-lysosome Fusion Midbody Abscission Protein Localization To Chromatin Multivesicular Body Sorting Pathway Membrane Fission Autophagosome Maturation Regulation Of Mitotic Spindle Assembly Late Endosome To Lysosome Transport ESCRT III Complex Disassembly
Pathways		Budding and maturation of HIV virion Macroautophagy Pyroptosis Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 20732625) Brain morphology (MOSTest) ( 32665545) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: CREB3 OGT PAFAH1B3 TRIM55 TRIM63 USP8
Entrez ID		91782
HPRD ID		14534
Ensembl ID		ENSG00000147457
Uniprot IDs		B3KMN6 B3KRZ9 B3KUH0 Q8WUX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Negative Regulation Of Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Deacetylase Activity Platelet-activating Factor Acetyltransferase Activity 1-alkyl-2-acetylglycerophosphocholine Esterase Activity 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Protein Modification Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Intracellular Signal Transduction Regulation Of Generation Of Precursor Metabolites And Energy Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Protein Catabolic Process Protein O-acetylglucosaminyltransferase Activity Response To Hormone Post-translational Protein Modification Negative Regulation Of Lysosomal Protein Catabolic Process Intracellular Signaling Cassette Response To Glucocorticoid Response To Corticosteroid Response To Steroid Hormone Positive Regulation Of Amyloid Fibril Formation Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission CCR1 Chemokine Receptor Binding Release From Viral Latency Diapedesis Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Skeletal Muscle Atrophy Skeletal Muscle Adaptation Striated Muscle Atrophy Regulation Of Transcription By Glucose Muscle Atrophy CAMP Response Element Binding Protein Binding NSL Complex Regulation Of Lysosomal Protein Catabolic Process Signal Transduction Titin Binding Contractile Muscle Fiber Cytoplasm Regulation Of Small Molecule Metabolic Process Induction Of Positive Chemotaxis Microtubule K63-linked Deubiquitinase Activity
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