ATP23 and KLC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP23	KLC3
Description		ATP23 metallopeptidase and ATP synthase assembly factor homolog	kinesin light chain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Plasma Membrane DNA-dependent Protein Kinase-DNA Ligase 4 Complex Cell Junction	Cytoplasm Mitochondrion Cytoskeleton Kinesin Complex Microtubule Motile Cilium Ciliary Rootlet Neuron Projection
	Molecular Function	Metalloendopeptidase Activity DNA-dependent Protein Kinase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Protein Binding Microtubule Binding Kinesin Binding
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Proteolysis Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Protein Processing	Microtubule-based Movement Spermatogenesis Spermatid Development Axo-dendritic Transport Cell Differentiation Sperm Mitochondrial Sheath Assembly
Pathways			MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS			Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Body mass index ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971)
Interacting Genes		31 interacting genes: ABI2 ACTN3 AIRIM AP2B1 ATG5 BAG4 BCL6 CCDC120 CSTF2 CSTF2T CTNNA3 DUSP21 EXOC8 FOXH1 FOXI1 FRS3 GLYCTK GUCD1 HNRNPF HOXA1 HR KLC3 KRTAP10-1 MGAT5B PLSCR4 PPP1R16A STK16 TRIP6 TSSK3 XRCC6 ZIC1	41 interacting genes: ABI3 ATP23 BBS5 BICDL2 CBY2 CCNH CENPP CEP57L1 CROCC CT55 DTX2 GEM IHO1 IMP3 KDM1A KIF5A KIF5B KIF5C KLHL21 KRT13 KRT15 MBIP NDC80 NECAB2 NEFL PCBD2 PDE4DIP QARS1 SMARCB1 SNAP47 STX11 TCF4 USHBP1 VPS52 WAC WASHC1 YWHAG YWHAH YWHAQ ZNF417 ZNF572
Entrez ID		91419	147700
HPRD ID		17256	03212
Ensembl ID		ENSG00000166896	ENSG00000104892
Uniprot IDs		Q9Y6H3	Q6P597
PDB IDs
Enriched GO Terms of Interacting Partners?			Ciliary Rootlet Organelle Localization Establishment Of Organelle Localization Anterograde Dendritic Transport Of Neurotransmitter Receptor Complex Anterograde Axonal Protein Transport Anterograde Dendritic Transport Protein Transport Along Microtubule Anterograde Axonal Transport Establishment Of Vesicle Localization Identical Protein Binding Dendritic Transport Vesicle Localization Plus-end-directed Microtubule Motor Activity Axon Cytoplasm Retrograde Axonal Transport Axonal Transport Dendrite Cytoplasm Axo-dendritic Transport Postsynaptic Cytosol Protein Binding Retrograde Neuronal Dense Core Vesicle Transport Transport Along Microtubule Organelle Transport Along Microtubule Synaptic Vesicle Transport Cytoskeleton-dependent Intracellular Transport Cytoskeleton Vesicle Transport Along Microtubule Kinesin Complex Microtubule-based Transport Establishment Of Localization In Cell Dense Core Granule Cytoskeletal Transport Receptor Localization To Synapse Presynapse Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cytosolic Transport Vesicle Fusion To Plasma Membrane Vesicle Cytoskeletal Trafficking Microtubule Binding Microtubule Motor Activity Intracellular Transport Protein Localization To Synapse Microtubule-based Process Synaptic Vesicle Membrane Organization Intracellular Protein Localization Insulin-like Growth Factor Receptor Binding Establishment Of Protein Localization Intermediate Filament Organization Secretory Granule Localization Protein Localization To Cell Junction Intermediate Filament Cytoskeleton Organization
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