ATP23 and DUSP21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP23	DUSP21
Description		ATP23 metallopeptidase and ATP synthase assembly factor homolog	dual specificity phosphatase 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Cytosol Plasma Membrane DNA-dependent Protein Kinase-DNA Ligase 4 Complex Cell Junction	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytoskeleton Cilium Membrane Motile Cilium Sperm Flagellum Cell Projection Axonemal A Tubule Inner Sheath
	Molecular Function	Metalloendopeptidase Activity DNA-dependent Protein Kinase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Metal Ion Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
	Biological Process	Double-strand Break Repair Via Nonhomologous End Joining Proteolysis Mitochondrial Proton-transporting ATP Synthase Complex Assembly Mitochondrial Protein Processing	Flagellated Sperm Motility Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: ABI2 ACTN3 AIRIM AP2B1 ATG5 BAG4 BCL6 CCDC120 CSTF2 CSTF2T CTNNA3 DUSP21 EXOC8 FOXH1 FOXI1 FRS3 GLYCTK GUCD1 HNRNPF HOXA1 HR KLC3 KRTAP10-1 MGAT5B PLSCR4 PPP1R16A STK16 TRIP6 TSSK3 XRCC6 ZIC1	33 interacting genes: APP ATP23 BPIFA1 CPNE7 CTBP2 EPHA3 EPHA5 ERBB3 ERBB4 EYA2 FAAP20 GET4 GORASP2 IGF1R KLHL20 KRT33B KRTAP11-1 MAP2K5 MYO15B OIP5 POU4F3 PTK7 RFX6 RGS2 ROR1 ROR2 SUOX TEX11 TOX3 TRAF1 UBQLN2 USP2 ZMAT1
Entrez ID		91419	63904
HPRD ID		17256	06494
Ensembl ID		ENSG00000166896	ENSG00000189037
Uniprot IDs		Q9Y6H3	Q9H596
PDB IDs
Enriched GO Terms of Interacting Partners?			Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Kinase Activity Receptor Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Axon Neuregulin Receptor Activity Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway GPI-linked Ephrin Receptor Activity Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Coreceptor Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Glial Cell Development Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Ephrin Receptor Activity Transmembrane-ephrin Receptor Activity Cellular Developmental Process Insulin Receptor Binding Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Neuron Projection Guidance Axon Guidance ERBB2 Signaling Pathway Establishment Of Planar Polarity ATP Binding Epithelial Cell Differentiation Amyloid-beta Complex Apoptotic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Programmed Cell Death Positive Regulation Of Toll Signaling Pathway Cell Death Positive Regulation Of DNA-binding Transcription Factor Activity Heart Development Cranial Nerve Development Establishment Of Planar Polarity Involved In Nephron Morphogenesis Insulin-like Growth Factor Receptor Signaling Pathway Wnt-protein Binding Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Sulfite Oxidase Activity Type II Interferon Binding Meiotic Gene Conversion
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