USP2 and GOLGA6L9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		USP2	GOLGA6L9
Description		ubiquitin specific peptidase 2	golgin A6 family like 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Cyclin Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Proteolysis Muscle Organ Development Protein Deubiquitination Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Locomotor Rhythm Positive Regulation Of Mitotic Cell Cycle Rhythmic Process Circadian Behavior Protein Stabilization Regulation Of Signal Transduction By P53 Class Mediator
Pathways		TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway Ub-specific processing proteases Regulation of TP53 Degradation
Drugs
Diseases
GWAS		Refractive error ( 32231278) Serum uric acid levels ( 30993211) Urate levels ( 23263486 31578528 31985003)	Tourette syndrome ( 30818990)
Interacting Genes		178 interacting genes: ABI2 ACTN1 ACTN2 ACTN3 APP AR ASPG ATG14 ATN1 AURKA BAP1 BCAR1 BCL2L2-PABPN1 BEGAIN BEND5 BICD2 BIRC7 BRCA1 CADPS CALCOCO2 CARD9 CBLC CCDC136 CCDC57 CCDC85B CCDC88B CDC34 CEP63 CEP70 CRACR2A CRACR2B CRY1 DCAF1 DDI1 DEPDC5 DISC1 DSCR4 DTX3 DUSP21 DYDC1 E2F4 EFHC2 EIF4ENIF1 ENPP1 ERBB2 EXOC5 EXOSC8 FANCD2 FBXW7 G3BP1 GEMIN4 GOLGA2 GOLGA6A GOLGA6L9 GPRASP3 GRB7 GRIPAP1 H2AC20 H2AC4 H2BC3 HOMER3 HOOK1 HOOK2 IHO1 IKBKG IKZF3 IL1RL2 INTS11 JAKMIP1 JRK KAZN KIFC3 KRT15 KRT27 KRT31 KRT33B KRT34 KRT35 KRT40 LHX3 LHX4 LMNA LMNB2 LNX2 LONRF1 LRSAM1 LZTS2 MALT1 MAP3K2 MDM2 MID2 MLKL MNAT1 MORN5 MRPL28 MTUS2 MYC NAB2 NDEL1 NEFL NFKB2 NOTCH1 NR3C1 OIP5 OPTN ORC3 ORC5 PALB2 PCGF6 PEX5 PIBF1 PICK1 PIK3R3 PLA2G2A PLEKHG4 PML PNMA1 POU2AF1 PRDM14 PRR5L RABEP1 RAD18 RBCK1 RFX6 RNF125 RNF126 RNF144B RNF149 RNF166 RUNDC3A S100A10 SH2B2 SLC2A1 SMAD7 SNCA SORBS3 SPAG8 SPDYE4 STAT5B TAX1BP1 TEKT4 TFIP11 TGFBR1 TLE5 TNFAIP2 TRAF1 TRAF2 TRAF6 TRAIP TRIM21 TRIM23 TRIM27 TRIM34 TRIM35 TRIM39 TRIM46 TRIM5 TRIM50 TRIM54 TRIM63 TRIM74 TRIM8 TRIM9 TRIP6 UBC UBE2S UBOX5 USHBP1 USP15 USP21 USP54 VCAM1 VPS28 VPS52 ZAP70 ZBED1 ZIM2 ZRANB1	215 interacting genes: AIRIM ANKRD11 ARHGAP9 ASXL1 ATP6V1G1 ATPAF2 ATXN7L2 AVPI1 BAG6 BAHD1 BANP BCL6B BHLHA9 BYSL C1orf35 C22orf15 C3 CABP2 CATIP CAVIN3 CBX8 CCDC116 CCDC120 CCDC146 CCDC185 CCDC187 CCHCR1 CDC37 CDC73 CDK18 CEP72 CEP95 CNNM3 CWF19L2 DAXX DEF6 DENND5A DES DOCK2 DPF2 DUSP26 EAF1 EIF3D ENKD1 FAAP20 FAM107A FAM110A FAM161A FAM161B FBXO28 FEM1A FLYWCH1 FXN GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GTF2B HAPLN2 HBZ HDAC4 HDAC7 HGS HOXB5 HOXB9 HOXC8 IL16 INO80B ISCU JMY JRK KANK2 KCTD9 KLHL35 KRT1 KRT75 LAGE3 LENG1 LGALS4 LMO3 LMO4 LYSMD1 M1AP MAB21L2 MBD3 MBD3L2 MFAP1 MOS MRPL11 MYOZ3 NAB2 NDUFAF3 NSMF NTAQ1 NXF1 NXT2 ORC1 PATZ1 PCDHB14 PHF1 PIN1 PKN1 PNMA5 POLL POLR1C POU6F2 PPP1R18 PRKAB2 PRPF18 PRPF31 PWWP2B RANBP3L RASSF10 RIN1 RLN1 RNF39 RNPS1 RTP5 SCAND1 SCNM1 SH2D4A SHC3 SLIRP SLX9 SMARCD1 SMARCE1 SNAI1 SSX5 STAMBPL1 STK25 SUOX SUV39H1 SUV39H2 TACO1 TBC1D30 TCEANC TEAD4 THAP7 TJAP1 TLE5 TLX3 TMSB4X TPRX1 TRAF3IP3 TRAF4 TRIM14 TSEN54 TSFM TSGA10IP TSPYL4 TTC23 TXN2 TYK2 UBASH3A UBL4B UBTFL1 USHBP1 USP2 VEZF1 WDR25 ZBTB16 ZBTB24 ZFHX3 ZFP1 ZGPAT ZKSCAN3 ZMAT2 ZNF124 ZNF155 ZNF165 ZNF17 ZNF20 ZNF205 ZNF230 ZNF250 ZNF264 ZNF32 ZNF329 ZNF35 ZNF410 ZNF414 ZNF417 ZNF438 ZNF444 ZNF446 ZNF479 ZNF48 ZNF490 ZNF497 ZNF524 ZNF552 ZNF557 ZNF574 ZNF578 ZNF580 ZNF581 ZNF587 ZNF599 ZNF624 ZNF628 ZNF629 ZNF648 ZNF669 ZNF696 ZNF764 ZNF785 ZNF792 ZNF80 ZNF835 ZNF837 ZNF844 ZNHIT1 ZSCAN23 ZSCAN26
Entrez ID		9099	440295
HPRD ID		05287
Ensembl ID		ENSG00000036672	ENSG00000197978
Uniprot IDs		O75604	A6NEM1
PDB IDs		2HD5 2IBI 3NHE 3V6C 3V6E 5XU8 5XVE 6DGF
Enriched GO Terms of Interacting Partners?		Ubiquitin Protein Ligase Activity Post-translational Protein Modification Protein Modification By Small Protein Conjugation Protein Ubiquitination Identical Protein Binding Ubiquitin-protein Transferase Activity Protein Modification Process Cytoskeleton Cytoplasm Cytosol Zinc Ion Binding Regulation Of Apoptotic Process Innate Immune Response Suppression Of Viral Release By Host Regulation Of Programmed Cell Death Protein Binding Defense Response To Other Organism Immune Response Immune System Process Protein Metabolic Process Defense Response To Symbiont Organelle Organization Response To External Biotic Stimulus Protein Polyubiquitination Response To Other Organism Metal Ion Binding Positive Regulation Of Catabolic Process Cytoskeleton Organization Cell Death Ubiquitin Protein Ligase Binding Defense Response Proteolysis Involved In Protein Catabolic Process Transferase Activity Transcription Coactivator Activity Programmed Cell Death Intermediate Filament Cytoskeleton Organization Apoptotic Process Intermediate Filament-based Process Regulation Of Metabolic Process Response To Stress Regulation Of Macromolecule Metabolic Process Intermediate Filament Organization Regulation Of Signal Transduction Protein K63-linked Ubiquitination Negative Regulation Of Signal Transduction Positive Regulation Of Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Signaling Signaling Adaptor Activity Negative Regulation Of Programmed Cell Death	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Zinc Ion Binding Regulation Of RNA Metabolic Process Nucleus DNA Binding Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific Double-stranded DNA Binding Nucleoplasm Nuclear Speck
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?