SART1 and SNRNP200

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid, pull down)

		SART1	SNRNP200
Gene Name		squamous cell carcinoma antigen recognized by T cells	small nuclear ribonucleoprotein 200kDa (U5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Cajal Body U4/U6 X U5 Tri-snRNP Complex Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Maturation Of 5S RRNA Cell Cycle Arrest MRNA Cis Splicing, Via Spliceosome Positive Regulation Of Cytotoxic T Cell Differentiation Intrinsic Apoptotic Signaling Pathway	Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP CHERP IGHE MFAP1 RBM25 SNRNP200 SNW1 SRSF4 SUMO1 UBL5 WBP4 ZCCHC10	19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG
Entrez ID		9092	23020
HPRD ID		10440	03391
Ensembl ID		ENSG00000175467	ENSG00000144028
Uniprot IDs		O43290	O75643
PDB IDs			2Q0Z 4F91 4F92 4F93 4KIT
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of RNA Splicing RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression MRNA Cis Splicing, Via Spliceosome Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA 3'-end Processing Positive Regulation Of Vitamin D Receptor Signaling Pathway Cis Assembly Of Pre-catalytic Spliceosome Synaptic Growth At Neuromuscular Junction RNA 3'-end Processing Collateral Sprouting In Absence Of Injury PML Body Organization Notch Signaling Pathway Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization To Nuclear Pore Regulation Of Vitamin D Receptor Signaling Pathway Axon Choice Point Recognition Protein Localization To Nuclear Envelope Positive Regulation Of NFAT Protein Import Into Nucleus Intracellular Receptor Signaling Pathway Neuron Remodeling Positive Regulation By Host Of Viral Transcription Innate Immune Response	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication
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