SNRNP200 and SNRNP40

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid, biochemical)

		SNRNP200	SNRNP40
Gene Name		small nuclear ribonucleoprotein 200kDa (U5)	small nuclear ribonucleoprotein 40kDa (U5)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Catalytic Step 2 Spliceosome	Nucleoplasm U5 SnRNP Small Nucleolar Ribonucleoprotein Complex Cytoplasm Catalytic Step 2 Spliceosome
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding ATP-dependent Helicase Activity Identical Protein Binding Poly(A) RNA Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Alcohol dependence ( 23455491)
Protein-Protein Interactions		19 interactors: APC BARD1 BRCA1 CHMP1B ECT2 ERG GRB2 LSM8 MEGF10 PIN1 PRPF8 RNF113A SART1 SF3B2 SMNDC1 SNRNP40 USP19 YWHAB YWHAG	6 interactors: ACP5 APP DDR1 DHX16 EFTUD2 SNRNP200
Entrez ID		23020	9410
HPRD ID		03391	08481
Ensembl ID		ENSG00000144028	ENSG00000060688
Uniprot IDs		O75643	A0MNP2 B4DQJ1 Q96DI7
PDB IDs		2Q0Z 4F91 4F92 4F93 4KIT
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Organelle Organization RNA Splicing Regulation Of Cell Cycle MRNA Processing Regulation Of Cell Cycle Process MRNA Metabolic Process Cell Cycle RNA Processing Regulation Of Microtubule Cytoskeleton Organization Apoptotic Process Apoptotic Signaling Pathway Programmed Cell Death Cell Cycle Process Regulation Of Microtubule-based Process Cell Death Death Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Protein K6-linked Ubiquitination Regulation Of Cytoskeleton Organization Regulation Of Phosphorylation Regulation Of Cell Division Regulation Of Cellular Component Organization Cytokinesis Positive Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Protein Metabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Cycle Arrest Response To Ionizing Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Protein Localization Intracellular Signal Transduction Regulation Of Intracellular Transport Cellular Component Assembly Ribonucleoprotein Complex Assembly Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cellular Protein Metabolic Process Cellular Response To Organonitrogen Compound Spliceosomal SnRNP Assembly Regulation Of Apoptotic Process Regulation Of Centrosome Duplication	MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Smooth Muscle Cell-matrix Adhesion Cis Assembly Of Pre-catalytic Spliceosome Negative Regulation Of Superoxide Anion Generation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Riboflavin Metabolic Process Axon Choice Point Recognition Heterocycle Metabolic Process Collagen-activated Signaling Pathway Cellular Nitrogen Compound Metabolic Process Neuron Remodeling Smooth Muscle Cell Migration Regulation Of Extracellular Matrix Disassembly Regulation Of Superoxide Anion Generation Negative Regulation Of Interleukin-1 Beta Production Nitrogen Compound Metabolic Process Negative Regulation Of Nitric Oxide Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization RNA Metabolic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process MRNA Cis Splicing, Via Spliceosome Cellular Copper Ion Homeostasis Negative Regulation Of Interleukin-12 Production Wound Healing, Spreading Of Cells Regulation Of Extracellular Matrix Organization Gene Expression Muscle Cell Migration Copper Ion Homeostasis Suckling Behavior Cellular Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Mammary Gland Lobule Development Mammary Gland Alveolus Development Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Branching Involved In Mammary Gland Duct Morphogenesis
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