TCEAL8 and CD209

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TCEAL8	CD209
Description		transcription elongation factor A like 8	CD209 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Extracellular Region Cytoplasm Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Host Cell
	Molecular Function	Protein Binding	Virus Receptor Activity Protein Binding D-mannose Binding Carbohydrate Binding Pattern Recognition Receptor Activity Peptide Antigen Binding Virion Binding Metal Ion Binding
	Biological Process		Adaptive Immune Response Immune System Process Endocytosis Immune Response Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Cell-cell Recognition Virion Attachment To Host Cell Viral Genome Replication Antigen Processing And Presentation Intracellular Signal Transduction Positive Regulation Of T Cell Proliferation Regulation Of T Cell Proliferation Innate Immune Response Symbiont Entry Into Host Cell Peptide Antigen Transport Intracellular Transport Of Virus B Cell Adhesion Positive Regulation Of Viral Life Cycle
Pathways			CD209 (DC-SIGN) signaling Butyrophilin (BTN) family interactions RSV-host interactions
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		5 interacting genes: APP CCDC24 CD209 COMMD1 GRB2	10 interacting genes: CEACAM1 CLEC4M CLU CRYAA ICAM2 ICAM3 IFT20 ITGAM TCEAL8 VAC14
Entrez ID		90843	30835
HPRD ID		06656	05241
Ensembl ID		ENSG00000180964	ENSG00000090659
Uniprot IDs		Q8IYN2	B2R907 B4E2A8 M0R0P0 Q9NNX6 X6RB12
PDB IDs			1K9I 1SL4 1SL5 2B6B 2IT5 2IT6 2XR5 2XR6 6GHV 7NL6 7NL7 9EMQ 9EMR 9EMS
Enriched GO Terms of Interacting Partners?		Copper Ion Homeostasis Ephrin Receptor Binding Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Cell Activation Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endocytosis Positive Regulation Of Reactive Oxygen Species Metabolic Process Vesicle-mediated Transport Glial Cell Development Guanyl-nucleotide Exchange Factor Adaptor Activity B Cell Adhesion Positive Regulation Of Cholesterol Import Acetylcholine Receptor Activator Activity PTB Domain Binding Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Cell Activation Defense Response To Symbiont Cell Recognition Recycling Endosome Defense Response To Other Organism Endosome Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Lipoprotein Particle Import Into Cell Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Grb2-EGFR Complex Peptide Antigen Transport Negative Regulation Of Hypoxia-inducible Factor-1alpha Signaling Pathway Positive Regulation Of Endosome To Plasma Membrane Protein Transport Positive Regulation Of Supramolecular Fiber Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Regulation Of Plasma Lipoprotein Particle Levels Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation	Cell-cell Adhesion Endocytosis Cell Adhesion Amyloid-beta Clearance Integrin Binding Receptor-mediated Endocytosis Microglial Cell Activation Regulation Of Vesicle-mediated Transport Leukocyte Activation Involved In Inflammatory Response Import Into Cell Signaling Receptor Activity Macrophage Activation Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction PAS Complex Tertiary Granule Membrane Microvillus Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Insulin Receptor Internalization Negative Regulation Of Cytotoxic T Cell Degranulation Negative Regulation Of Hepatocyte Proliferation Regulation Of Transport Regulation Of Leukocyte Mediated Cytotoxicity Specific Granule Membrane Integrin-mediated Signaling Pathway Cell Periphery Amyloid-beta Binding Negative Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of Neurofibrillary Tangle Assembly Central Nervous System Myelin Maintenance Immune Complex Clearance Integrin AlphaM-beta2 Complex Positive Regulation Of Neutrophil Degranulation Response To Curcumin Vertebrate Eye-specific Patterning ICAM-3 Receptor Activity Peptide Antigen Transport Kinociliary Basal Body Opsin Transport Intraciliary Transport Particle Unfolded Protein Binding Insulin Catabolic Process Regulation Of Regulated Secretory Pathway Regulation Of Receptor-mediated Endocytosis Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Chromaffin Granule Negative Regulation Of Dopamine Metabolic Process Positive Regulation Of Microglial Cell Mediated Cytotoxicity Complement-mediated Synapse Pruning Opsin Binding
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