CLDN8 and SMIM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN8	SMIM3
Description		claudin 8	small integral membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Bicellular Tight Junction Membrane Basolateral Plasma Membrane Apicolateral Plasma Membrane Anchoring Junction	Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly
Pathways		Tight junction interactions
Drugs
Diseases
GWAS		Response to statin therapy ( 20339536)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)
Interacting Genes		12 interacting genes: ADAM32 ARL13B CLEC17A ERGIC3 KASH5 OPRM1 PKMYT1 SMIM3 SYNE4 TJP1 TMEM80 TRARG1	52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1
Entrez ID		9073	85027
HPRD ID		10835	12212
Ensembl ID		ENSG00000156284	ENSG00000256235
Uniprot IDs		A0A0K0K1I9 P56748	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Nuclear Outer Membrane	Membrane Plasma Membrane Bleb Assembly Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Endoplasmic Reticulum Membrane Sarcoglycan Complex Fucose Binding Myelination Pattern Recognition Receptor Activity Bicellular Tight Junction Assembly Protein Binding Structural Constituent Of Myelin Sheath Schmidt-Lanterman Incisure Tight Junction Assembly Bicellular Tight Junction Central Nervous System Myelination Tight Junction Organization
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