CLDN10 and REEP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN10	REEP1
Description		claudin 10	receptor accessory protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Bicellular Tight Junction Membrane Tight Junction Anchoring Junction	Cytoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytoplasmic Microtubule Membrane Mitochondrial Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Structural Molecule Activity Protein Binding Identical Protein Binding Paracellular Tight Junction Channel Activity	Protein Binding Microtubule Binding Olfactory Receptor Binding
	Biological Process	Monoatomic Ion Transport Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Regulation Of Monoatomic Ion Transport Bicellular Tight Junction Assembly Paracellular Transport	Protein Insertion Into Membrane Endoplasmic Reticulum Tubular Network Organization
Pathways		Tight junction interactions Developmental Lineage of Pancreatic Ductal Cells	Expression and translocation of olfactory receptors
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Dental caries (decayed and filled deciduous teeth) ( 31533690) Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483) Psychosis proneness (hypomanic personality scale) ( 28525603)	Atrial fibrillation ( 29892015 30061737) Facial emotion recognition (sad faces) ( 28608620) Night sleep phenotypes ( 27126917)
Interacting Genes		11 interacting genes: BEST2 CISD2 HSD17B13 HTR4 LMNA OPRM1 PEX12 REEP1 TMEM14B TMEM9 VKORC1	7 interacting genes: CLDN10 CSRP1 STX7 TMEM100 TMEM42 TMEM97 UNC93B1
Entrez ID		9071	65055
HPRD ID		13063	07810
Ensembl ID		ENSG00000134873	ENSG00000068615
Uniprot IDs		P78369	A0A1C7CYY3 A0A2R8Y6K6 A0A8I5KRE1 A0A8I5QKJ2 Q9H902
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Large Intestinal Transit Morphine Receptor Activity Negative Regulation Of Wnt Protein Secretion Beta-endorphin Receptor Activity Intracellularly Ligand-gated Monoatomic Ion Channel Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Endoplasmic Reticulum Cellular Response To Morphine Peroxisomal Importomer Complex Ligand-gated Monoatomic Cation Channel Activity Bicarbonate Channel Activity Ligand-gated Monoatomic Anion Channel Activity Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Steroid Dehydrogenase Activity
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