CLDN12 and STRN4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CLDN12	STRN4
Description		claudin 12	striatin 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Membrane Lateral Plasma Membrane Tight Junction Anchoring Junction Cell Periphery	Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Maintenance Of Blood-brain Barrier Tight Junction Assembly	Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways		Tight junction interactions
Drugs
Diseases
GWAS			Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Primary sclerosing cholangitis ( 23603763)
Interacting Genes		4 interacting genes: ECHS1 SEC13 STRN4 TRARG1	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		9069	29888
HPRD ID		13064	18125
Ensembl ID		ENSG00000157224	ENSG00000090372
Uniprot IDs		B2R687 P56749	F5GYK2 Q59GV6 Q9NRL3
PDB IDs
Enriched GO Terms of Interacting Partners?		3-hydroxypropionyl-CoA Dehydratase Activity Crotonyl-CoA Hydratase Activity Enoyl-CoA Hydratase Activity Delta(3)-delta(2)-enoyl-CoA Isomerase Activity 3-hydroxyacyl-CoA Dehydratase Activity Vesicle Organization Nuclear Pore Outer Ring COPII-coated Vesicle Budding GATOR2 Complex Armadillo Repeat Domain Binding Glucose Import In Response To Insulin Stimulus Vesicle Fusion To Plasma Membrane Branched-chain Amino Acid Catabolic Process COPII-coated Vesicle Cargo Loading COPII Vesicle Coat Regulation Of Modification Of Synaptic Structure FAR/SIN/STRIPAK Complex Regulation Of Modification Of Postsynaptic Structure Endosome To Plasma Membrane Protein Transport D-glucose Import Branched-chain Amino Acid Metabolic Process Intracellular Protein Transport Negative Regulation Of Hippo Signaling Membrane Organization Protein Exit From Endoplasmic Reticulum Vesicle Budding From Membrane Vesicle Cargo Loading Protein Phosphatase 2A Binding D-glucose Transmembrane Transport Hexose Transmembrane Transport	MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential
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