IFT20 and RALGPS2

		IFT20	RALGPS2
Description		intraflagellar transport 20	Ral GEF with PH domain and SH3 binding motif 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Vesicle Photoreceptor Outer Segment Manchette Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Centriole Cytoskeleton Microvillus Cilium Intraciliary Transport Particle Intraciliary Transport Particle B Cytoplasmic Vesicle Motile Cilium Photoreceptor Connecting Cilium Stereocilium Ciliary Basal Body Cell Projection Neuron Projection Dendrite Terminus Ciliary Tip Ciliary Base Non-motile Cilium Kinociliary Basal Body	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Opsin Binding Protein Binding Small GTPase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Neurogenesis Cell Projection Organization Cell Differentiation Protein Localization To Golgi Apparatus Intraciliary Anterograde Transport Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Cilium Assembly Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Transmembrane Transport Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly	Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction
Pathways		Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 32771030)
Interacting Genes		46 interacting genes: ABI2 ABI3 AQP1 ATG16L1 BLOC1S6 C1orf216 CCHCR1 CD209 CLEC4M CORO1A CROCCP2 DTNBP1 EMILIN1 EXOC7 FAM81B FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KAT5 KDM8 KIF3B KNSTRN KPNA2 KRT13 KXD1 MED30 MIS18A NDC80 NUP54 NUP62 OXNAD1 PBX4 PPP1R11 PSMA1 PTPN12 RASSF4 SH3BP5 SYCE2 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17	4 interacting genes: OSBPL3 YWHAB YWHAG YWHAZ
Entrez ID		90410	55103
HPRD ID		17137	15206
Ensembl ID		ENSG00000109083	ENSG00000116191
Uniprot IDs		A0A087X2B4 Q8IY31	Q86X27
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Intracellular Transport Transport Along Microtubule Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cytoskeleton Organization Organelle Transport Along Microtubule Microtubule-based Transport Organelle Assembly Organelle Localization Establishment Of Organelle Localization Intracellular Transport Of Virus Cellular Localization Organelle Organization Host Cell Regulation Of Actin Nucleation SCAR Complex Axo-dendritic Transport Spindle Pole Vesicle Transport Along Microtubule BLOC-1 Complex Protein Transport Establishment Of Protein Localization Microtubule-based Movement Vesicle Cytoskeletal Trafficking Peptide Antigen Transport Viral Genome Replication Protein Binding Axonal Transport Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Arp2/3 Complex-mediated Actin Nucleation CGAS/STING Signaling Pathway Positive Regulation Of Aggrephagy Mitotic Centrosome Separation Nuclear Pore Central Transport Channel Spindle Organization Positive Regulation Of Cell Cycle Process Regulation Of Cytokinesis Vesicle-mediated Transport Cellular Component Assembly Synaptic Vesicle Transport Establishment Of Mitotic Spindle Orientation Positive Regulation Of Mitotic Cytokinetic Process Identical Protein Binding Membraneless Organelle Assembly Spindle Assembly Regulation Of Organelle Organization Cell Projection Morphogenesis Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin-based Cell Projection	Protein Sequestering Activity Phosphoserine Residue Binding Protein Domain Specific Binding Protein Targeting Negative Regulation Of Protein Localization To Nucleus Focal Adhesion Establishment Of Protein Localization Cellular Response To Glucose Starvation Negative Regulation Of TORC1 Signaling TORC1 Signaling Regulation Of Vacuole Organization TOR Signaling Negative Regulation Of TOR Signaling Melanosome Regulation Of TORC1 Signaling Intracellular Protein Localization Synaptic Target Recognition Opsin Transport Intraciliary Transport Particle Regulation Of Protein Localization To Nucleus Regulation Of TOR Signaling Protein Kinase C Inhibitor Activity Kinociliary Basal Body Vesicle Cellular Response To Starvation Opsin Binding Regulation Of Protein Localization Golgi Reassembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Dendrite Terminus Negative Regulation Of Protein Localization Negative Regulation Of Immune Response Response To Starvation Cellular Response To Nutrient Levels Establishment Of Golgi Localization Sterol Transfer Activity Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphorylation-dependent Protein Binding Cadherin Binding Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Signal Transduction Vacuolar Membrane Negative Regulation Of Immune Response To Tumor Cell Regulation Of Lysosome Organization Golgi Localization Photoreceptor Cell Outer Segment Organization Negative Regulation Of Signal Transduction Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Protein Stability Insulin-like Growth Factor Receptor Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?