RALGPS2

Description		Ral GEF with PH domain and SH3 binding motif 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Small GTPase-mediated Signal Transduction Ras Protein Signal Transduction
Pathways
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systemic lupus erythematosus ( 32771030)
Novel Interacting Genes		1 novel interacting genes: IFT20
Interacting Genes		4 interacting genes: OSBPL3 YWHAB YWHAG YWHAZ
Entrez ID		55103
HPRD ID		15206
Ensembl ID		ENSG00000116191
Uniprot IDs		Q86X27
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Sequestering Activity Phosphoserine Residue Binding Protein Domain Specific Binding Protein Targeting Negative Regulation Of Protein Localization To Nucleus Focal Adhesion Establishment Of Protein Localization Cellular Response To Glucose Starvation Negative Regulation Of TORC1 Signaling TORC1 Signaling Regulation Of Vacuole Organization TOR Signaling Negative Regulation Of TOR Signaling Melanosome Regulation Of TORC1 Signaling Intracellular Protein Localization Synaptic Target Recognition Opsin Transport Intraciliary Transport Particle Regulation Of Protein Localization To Nucleus Regulation Of TOR Signaling Protein Kinase C Inhibitor Activity Kinociliary Basal Body Vesicle Cellular Response To Starvation Opsin Binding Regulation Of Protein Localization Golgi Reassembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Dendrite Terminus Negative Regulation Of Protein Localization Negative Regulation Of Immune Response Response To Starvation Cellular Response To Nutrient Levels Establishment Of Golgi Localization Sterol Transfer Activity Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphorylation-dependent Protein Binding Cadherin Binding Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Signal Transduction Vacuolar Membrane Negative Regulation Of Immune Response To Tumor Cell Regulation Of Lysosome Organization Golgi Localization Photoreceptor Cell Outer Segment Organization Negative Regulation Of Signal Transduction Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Protein Stability Insulin-like Growth Factor Receptor Binding
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