THAP3 and NUTF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		THAP3	NUTF2
Description		THAP domain containing 3	nuclear transport factor 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nuclear Pore Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Membrane Nuclear Pore Central Transport Channel Extracellular Exosome
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Structural Constituent Of Nuclear Pore Small GTPase Binding Identical Protein Binding Nuclear Import Signal Receptor Activity
	Biological Process	Positive Regulation Of Transcription By RNA Polymerase II	Protein Import Into Nucleus Protein Export From Nucleus Nucleocytoplasmic Transport Protein Transport MRNA Transport Protein Localization To Nuclear Pore
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Schizophrenia ( 33169155)	Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		6 interacting genes: APP NUTF2 SPTBN1 TRIM55 TRIM63 UBL5	48 interacting genes: BEND7 BRWD1 CAMK2G CCDC106 CCDC150 CCDC158 CEBPA CHCHD3 CHMP4A CKMT1A CKMT1B CLPP FAM50B HMG20A HMG20B KHDC4 KRT86 KRTAP9-8 LASP1 LCE1C LCE5A LENG1 LUC7L2 MRNIP MYOZ3 NME1 NME4 NRIP3 NUP54 NUP62 PAX4 PBX4 PCNA PFKP PHF11 PPP1R16A PTMA RAN RPRD1B SPATC1L SPRY4 TEX35 THAP11 THAP3 TLE5 UBAP2 YAF2 ZMAT2
Entrez ID		90326	10204
HPRD ID		18178	12050
Ensembl ID		ENSG00000041988	ENSG00000102898
Uniprot IDs		Q8WTV1	P61970
PDB IDs			1GY5
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Response To Interleukin-1 Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Amylin Binding Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction M Band Acetylcholine Receptor Activator Activity PTB Domain Binding Innate Immune Response Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Generation Of Precursor Metabolites And Energy Central Nervous System Formation Protein Localization To Nuclear Pore Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Central Nervous System Development Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Defense Response To Symbiont Axon Midline Choice Point Recognition Defense Response To Other Organism Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Skeletal Muscle Atrophy Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Nuclear Pore Central Transport Channel Axon Choice Point Recognition	Protein Binding Protein-containing Complex Binding Phosphocreatine Biosynthetic Process Creatine Kinase Activity GTP Metabolic Process Nuclear Pore Nuclear Pore Central Transport Channel Nucleus UTP Biosynthetic Process GTP Biosynthetic Process UTP Metabolic Process Nucleoplasm Protein Hexamerization Negative Regulation Of Protein Sumoylation Male Germ Cell Nucleus CTP Biosynthetic Process CTP Metabolic Process
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