SYS1 and TM4SF19

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		SYS1	TM4SF19
Description		SYS1 golgi trafficking protein	transmembrane 4 L six family member 19
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane	Cytoplasm Lysosome Lysosomal Membrane Cytoskeleton Actin Cytoskeleton Membrane Filopodium Cell Projection
	Molecular Function	Protein Binding	Protein Binding Protein Homodimerization Activity
	Biological Process	Golgi To Endosome Transport Protein Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport	Positive Regulation Of Osteoclast Differentiation
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)
Interacting Genes		20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35H1 TM4SF19 TMEM248 TNFSF14	39 interacting genes: ABHD16A ARLN ATP6V0B BNIP1 C14orf180 CCDC167 CD79A CRK CTXN3 CYBC1 CYP4F2 DAPP1 ERG28 GET1 GIMAP1 GIMAP5 GOSR2 GPR152 HMOX1 NDUFA3 PLP2 PMP22 RIN3 SEC22B SERP2 SMIM1 STAT3 STX7 SYS1 TMEM167B TMEM179B TMEM237 TMEM42 TNS2 TSNARE1 UBE2J1 VAMP3 VAMP4 ZFPL1
Entrez ID		90196	116211
HPRD ID			14013
Ensembl ID		ENSG00000204070	ENSG00000145107
Uniprot IDs		Q8N2H4	B7ZW46 Q96DZ7
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-3-mediated Signaling Pathway Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Membrane SNAP Receptor Activity SNARE Complex Endoplasmic Reticulum Membrane Organelle Fusion Membrane Fusion Organelle Membrane Fusion Endoplasmic Reticulum Vesicle-mediated Transport Golgi Vesicle Transport Vesicle Fusion Golgi To Plasma Membrane Protein Transport Transport Vesicle Establishment Of Protein Localization To Plasma Membrane Vesicle Docking SNARE Complex Assembly Golgi To Plasma Membrane Transport SNARE Binding Golgi Membrane Endocytic Vesicle Membrane Organization Vesicle Organization Organelle Localization By Membrane Tethering Phagocytic Vesicle Membrane Protein Binding Membrane Docking
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