SYS1 and BTNL9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYS1	BTNL9
Description		SYS1 golgi trafficking protein	butyrophilin like 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Membrane Trans-Golgi Network Membrane	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Golgi To Endosome Transport Protein Transport Protein Localization To Golgi Apparatus Golgi To Plasma Membrane Protein Transport	Regulation Of Cytokine Production T Cell Receptor Signaling Pathway
Pathways		Retrograde transport at the Trans-Golgi-Network	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Free cholesterol levels in large HDL ( 29084231) Large HDL particle concentration ( 29084231) Malaria ( 31844061) Mean diameter of HDL particles ( 29084231) Phospholipid levels in large HDL ( 29084231)	Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: BTNL9 EBP ELOVL5 ERGIC3 FCER1G GLP1R HSD17B11 IL3RA KIR3DL3 MCFD2 MGST3 MRPS18B PSCA PVR SDCBP SLC30A8 SLC35H1 TM4SF19 TMEM248 TNFSF14	16 interacting genes: ADAM33 ADIPOQ CXCL9 CYB5B EDDM3A GIMAP5 JAGN1 NINJ2 PLPP6 RPRM SLC38A7 SLC61A1 SMIM3 SYS1 TNF UPK2
Entrez ID		90196	153579
HPRD ID			12550
Ensembl ID		ENSG00000204070	ENSG00000165810
Uniprot IDs		Q8N2H4	A0A1S5UZ21 Q6UXG8 Q8N324
PDB IDs
Enriched GO Terms of Interacting Partners?		Interleukin-3-mediated Signaling Pathway Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Positive Regulation Of Neutrophil Activation Regulation Of Neutrophil Activation Cytokine-mediated Signaling Pathway Membrane Negative Regulation Of Bile Acid Secretion Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Protein Localization To Plasma Membrane Response To Gram-negative Bacterium Negative Regulation Of Secretion Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Negative Regulation Of Blood Pressure Negative Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Renal Albumin Absorption Positive Regulation Of Metanephric Podocyte Development Positive Regulation Of Glycogen (starch) Synthase Activity Sperm Displacement L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Cytokine Activity Leukocyte Migration Neutrophil Migration Regulation Of Hormone Secretion Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Protein Localization To Cell Periphery Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Negative Regulation Of L-glutamate Import Across Plasma Membrane Positive Regulation Of Interleukin-8 Production Positive Regulation Of Fractalkine Production Positive Regulation Of Blood Microparticle Formation Response To Gold Nanoparticle Regulation Of D-glucose Import Positive Regulation Of Vitamin D Biosynthetic Process Negative Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Detection Of Oxidative Stress Negative Regulation Of Hormone Secretion Positive Regulation Of Chemokine Production Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Response To Other Organism
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