KIR3DX1 and FAM154A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KIR3DX1	FAM154A
Gene Name		killer cell immunoglobulin-like receptor, three domains, X1	family with sequence similarity 154, member A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function		Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS			Non-small cell lung cancer ( 23144319)
Protein-Protein Interactions		2 interactors: FAM154A IKBKG	18 interactors: ACTN2 CRK FAM124A FHL2 FHL3 GLYCTK HOXA1 KIR3DX1 LMO1 LMO2 MVP OSGIN1 POLR1C SORBS3 STK16 TRIP6 VPS28 ZMYND19
Entrez ID		90011	158297
HPRD ID		13328	16676
Ensembl ID			ENSG00000155875
Uniprot IDs			F6S232 Q8IYX7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of NIK/NF-kappaB Signaling B Cell Homeostasis NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Lymphocyte Homeostasis MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Leukocyte Homeostasis JNK Cascade Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway T Cell Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Antigen Receptor-mediated Signaling Pathway Activation Of MAPK Activity Activation Of Innate Immune Response Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway Establishment Of Vesicle Localization Negative Regulation Of Neuron Death Vesicle Localization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of MAP Kinase Activity Fc-epsilon Receptor Signaling Pathway MAPK Cascade Regulation Of I-kappaB Kinase/NF-kappaB Signaling Homeostasis Of Number Of Cells Regulation Of Innate Immune Response	Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Focal Adhesion Assembly Cell-substrate Adhesion Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Adherens Junction Assembly Regulation Of RNA Metabolic Process Cell-substrate Junction Assembly Positive Regulation Of Cellular Metabolic Process Optokinetic Behavior Abducens Nerve Formation Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Facial Nucleus Development Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Rhombomere 4 Development Atrial Cardiac Muscle Cell Development Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Semicircular Canal Formation Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Release Of Cytoplasmic Sequestered NF-kappaB Endosome Transport Via Multivesicular Body Sorting Pathway Microspike Assembly Late Endosome To Vacuole Transport Cell-matrix Adhesion Negative Regulation Of Protein Localization To Cell Surface Embryonic Neurocranium Morphogenesis Platelet Activation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Outer Ear Morphogenesis Actin Filament-based Process Cell Junction Assembly Semicircular Canal Morphogenesis Rhombomere Development Cellular Response To Thyroid Hormone Stimulus Viral Protein Processing Negative Regulation Of Cellular Metabolic Process
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