SIGLEC10 and LGALS3BP

Number of citations of the paper that reports this interaction (PubMedID 25320078)
66

Data Source:
BioGRID (pull down)

		SIGLEC10	LGALS3BP
Description		sialic acid binding Ig like lectin 10	galectin 3 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane	Extracellular Region Extracellular Space Membrane Extracellular Matrix Platelet Dense Granule Lumen Extracellular Exosome Blood Microparticle
	Molecular Function	Protein Binding Phosphatase Binding Carbohydrate Binding Sialic Acid Binding SH2 Domain Binding	Scavenger Receptor Activity Protein Binding
	Biological Process	Adaptive Immune Response Immune System Process Cell Adhesion Innate Immune Response Negative Regulation Of Inflammatory Response To Wounding	Cellular Defense Response Cell Adhesion Signal Transduction Vesicle-mediated Transport
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Platelet degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		3 interacting genes: FLNA LGALS3BP PTPN6	24 interacting genes: CD14 COL5A1 COL6A1 FBXO7 FN1 GALNT6 HSP90AA1 ITGA5 ITGA6 ITGAV ITGB1 LGALS1 LGALS3 NID1 PPIC SELE SIGLEC10 SIGLEC11 SIGLEC5 SIGLEC6 SIGLEC7 SIGLEC9 WNT4 XRN1
Entrez ID		89790	3959
HPRD ID		07307	02796
Ensembl ID		ENSG00000142512	ENSG00000108679
Uniprot IDs		B7ZL06 E9PL79 Q96LC7	Q08380
PDB IDs			1BY2 6GFB
Enriched GO Terms of Interacting Partners?		Megakaryocyte Development Platelet Aggregation Myeloid Cell Development Homotypic Cell-cell Adhesion Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Regulation Of Sequestering Of Calcium Ion Cell Adhesion Epididymis Development Hemopoiesis Glycoprotein Ib-IX-V Complex Regulation Of Monoatomic Ion Transmembrane Transport Cell-cell Junction Fc-gamma Receptor I Complex Binding Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Formation Of Radial Glial Scaffolds Tubulin Deacetylation Regulation Of Monoatomic Cation Transmembrane Transport Myb Complex Establishment Of Sertoli Cell Barrier CD27 Signaling Pathway Negative Regulation Of Mast Cell Activation Involved In Immune Response Protein Localization To Bicellular Tight Junction Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of Metal Ion Transport Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Neutrophil Activation Alpha-beta T Cell Receptor Complex Positive Regulation Of Integrin-mediated Signaling Pathway Cell-cell Adhesion Blood Coagulation, Intrinsic Pathway Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Cell Adhesion Positive Regulation Of Platelet Activation Actin Crosslink Formation Negative Regulation Of Transcription By RNA Polymerase I Extracellular Region Protein Deacetylation Extracellular Exosome Positive Regulation Of Cell Activation Regulation Of Monoatomic Ion Transport Platelet Dense Granule Lumen Non-membrane Spanning Protein Tyrosine Phosphatase Activity Regulation Of Inflammatory Response To Wounding Phosphorylation-dependent Protein Binding Negative Regulation Of Mast Cell Activation Inflammatory Response To Wounding Regulation Of Neutrophil Activation Negative Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Neutrophil Activation Involved In Immune Response	Cell Adhesion Sialic Acid Binding Carbohydrate Binding Wound Healing, Spreading Of Epidermal Cells Cell-matrix Adhesion Laminin Binding Integrin Complex Cell-substrate Adhesion Wound Healing, Spreading Of Cells Response To Muscle Activity Endodermal Cell Differentiation Integrin-mediated Signaling Pathway Proteoglycan Binding Regulation Of Cellular Component Organization Plasma Membrane Extracellular Matrix Cell Surface Cell Migration Integrin Binding Integrin Alpha6-beta1 Complex Integrin Alpha5-beta1 Complex Integrin Alphav-beta1 Complex Response To Activity Positive Regulation Of Cell Adhesion Cell Motility Basement Membrane Positive Regulation Of Cell Migration Regulation Of Locomotion Cell Adhesion Mediated By Integrin Regulation Of Cell Adhesion Secretory Granule Membrane Positive Regulation Of Cell Motility Calcium-independent Cell-matrix Adhesion Positive Regulation Of Locomotion Basement Membrane Organization Negative Regulation Of Apoptotic Signaling Pathway Heterotypic Cell-cell Adhesion Neuregulin Binding C-X3-C Chemokine Binding Cell-substrate Junction Assembly Cell-substrate Junction Organization Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Dendritic Cell Differentiation Signaling Receptor Activity Regulation Of Cell Migration Cell-cell Adhesion Mediated By Integrin Extracellular Exosome Endoplasmic Reticulum Lumen Extracellular Region Regulation Of Cell Motility
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