HBP1 and ANKRD2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
41

Data Source:
BioGRID (two hybrid)

		HBP1	ANKRD2
Description		HMG-box transcription factor 1	ankyrin repeat domain 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Speck	Euchromatin Nucleus Cytoplasm Cytosol PML Body I Band
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding	Protein Binding Structural Constituent Of Muscle Protein Kinase B Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Regulation Of Cell Cycle	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Muscle Contraction Muscle Organ Development Regulation Of Gene Expression Negative Regulation Of Myoblast Differentiation
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: ANKRD2 CASP8 CD2AP CREBBP EP300 ESR1 EWSR1 HDAC1 KIFBP RB1 RB1CC1 RBL2 SAP30 SIN3A SMAD1 TCF4 TMEM37 UBE2H WDR26 ZNF212	11 interacting genes: FCMR HBP1 HOMEZ LDB3 MAPK6 PML TCAP TP53 TTN YBX1 ZBTB3
Entrez ID		26959	26287
HPRD ID		13634	12460
Ensembl ID		ENSG00000105856	ENSG00000165887
Uniprot IDs		B4DJ36 O60381	A0A0A0MRN9 Q5T457 Q9GZV1
PDB IDs		2E6O 3QVE
Enriched GO Terms of Interacting Partners?		Transcription Regulator Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone H3K27 Acetyltransferase Activity Chromatin Cell Differentiation Sin3-type Complex Histone H3K18 Acetyltransferase Activity Transcription Corepressor Activity N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription By RNA Polymerase II Peptide Lactyltransferase (CoA-dependent) Activity Negative Regulation Of Stem Cell Population Maintenance Developmental Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II TFIIB-class Transcription Factor Binding Regulation Of Lipid Kinase Activity Rhythmic Process Regulation Of Gene Expression Transcription Coregulator Activity Regulation Of Macromolecule Biosynthetic Process Nucleus Cellular Developmental Process Protein-containing Complex Regulation Of RNA Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone Deacetylase Complex Positive Regulation Of Stem Cell Population Maintenance Transcription Coactivator Binding Chromatin Organization Regulation Of Protein Localization To Nucleus Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cell Differentiation Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II DNA Binding DNA-binding Transcription Factor Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Developmental Process P53 Binding Chromatin Remodeling Negative Regulation Of Biosynthetic Process N-terminal Protein Amino Acid Acetylation Regulation Of Stem Cell Population Maintenance	Titin-telethonin Complex Sarcomerogenesis Skeletal Muscle Myosin Thick Filament Assembly Myosin Filament Assembly Sarcomere Organization Skeletal Muscle Thin Filament Assembly Detection Of Muscle Stretch Muscle Alpha-actinin Binding Cardiac Myofibril Assembly Muscle Filament Sliding Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Telomere Maintenance Via Telomerase Z Disc Entrainment Of Circadian Clock By Photoperiod Cardiac Muscle Hypertrophy Response To Muscle Stretch I Band Photoperiodism Entrainment Of Circadian Clock Muscle Hypertrophy Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Myofibril Assembly Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Skeletal Muscle Contraction Negative Regulation Of Telomere Maintenance Actin-mediated Cell Contraction Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Via Telomerase Structural Constituent Of Muscle Cardiac Muscle Contraction Cardiac Cell Development Detection Of Mechanical Stimulus Somitogenesis DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Senescence Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Gamma Radiation Segmentation Negative Regulation Of Translation In Response To Oxidative Stress Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Helicase Activity Negative Regulation Of G1 To G0 Transition Heart Development Cardiac Muscle Tissue Morphogenesis High-affinity IgM Receptor Activity Actin Filament-based Movement Cellular Senescence
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