ADAM9 and SH3GLB1

Number of citations of the paper that reports this interaction (PMID 10531379)
35

Data Source:
HPRD (in vitro)

		ADAM9	SH3GLB1
Gene Name		ADAM metallopeptidase domain 9	SH3-domain GRB2-like endophilin B1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Focal Adhesion Cell Surface Integral Component Of Membrane Basolateral Plasma Membrane Intrinsic Component Of External Side Of Plasma Membrane Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Mitochondrial Outer Membrane Extracellular Vesicular Exosome
	Molecular Function	Metalloendopeptidase Activity Protein Kinase C Binding Integrin Binding Protein Binding Collagen Binding Metallopeptidase Activity Zinc Ion Binding SH3 Domain Binding Laminin Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Activation Of MAPKK Activity Membrane Protein Ectodomain Proteolysis Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Response To Manganese Ion Extracellular Matrix Disassembly Extracellular Matrix Organization Keratinocyte Differentiation Collagen Catabolic Process Cell Adhesion Mediated By Integrin Positive Regulation Of Cell Adhesion Mediated By Integrin Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Macrophage Fusion Response To Tumor Necrosis Factor Response To Laminar Fluid Shear Stress Monocyte Activation Response To Hydrogen Peroxide Positive Regulation Of Protein Secretion Positive Regulation Of Membrane Protein Ectodomain Proteolysis PMA-inducible Membrane Protein Ectodomain Proteolysis Response To Glucocorticoid Positive Regulation Of Keratinocyte Migration Response To Calcium Ion Cellular Response To Lipopolysaccharide	Apoptotic Process Positive Regulation Of Protein Oligomerization Protein Oligomerization
Pathways		Collagen degradation Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ITGA3 ITGA6 ITGAV MAD2L2 PRKCD SH3D19 SH3GLB1 SNX9 TNF	22 interactors: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CMTM5 DNM1 DNM2 FUNDC1 GADD45A GADD45G HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576
Entrez ID		8754	51100
HPRD ID		04091	15333
Ensembl ID		ENSG00000168615	ENSG00000097033
Uniprot IDs		Q13443	Q9Y371
PDB IDs		1M1V
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Membrane Protein Ectodomain Proteolysis Regulation Of Cellular Component Organization Regulation Of Cell Adhesion Negative Regulation Of Signal Transduction Leukocyte Migration Negative Regulation Of Signaling Regulation Of Protein Complex Assembly Extracellular Matrix Organization Regulation Of Cell-cell Adhesion Extracellular Structure Organization Positive Regulation Of Cell Adhesion Regulation Of Protein Catabolic Process Integrin-mediated Signaling Pathway Blood Coagulation Hemostasis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Lipid Storage Positive Regulation Of Protein Oligomerization Positive Regulation Of Cellular Protein Metabolic Process Cell-matrix Adhesion Positive Regulation Of Protein Complex Assembly Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Body Fluid Levels Regulation Of Protein Metabolic Process Wound Healing Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Protein Oligomerization Regulation Of Phosphorylation Cell-substrate Adhesion Positive Regulation Of Protein Catabolic Process Regulation Of Proteolysis Response To Wounding Regulation Of Phosphorus Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Phagocytosis Positive Regulation Of Proteolysis Regulation Of Signal Transduction Cell Migration Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Phosphorylation Regulation Of Lipid Catabolic Process Positive Regulation Of Cell Migration Regulation Of Lipid Storage Positive Regulation Of Cell Motility Cell Motility Positive Regulation Of Protein Modification Process Positive Regulation Of Lipid Biosynthetic Process Negative Regulation Of Apoptotic Process	Endocytosis Learning Regulation Of Cell Cycle Regulation Of Catalytic Activity Apoptotic Process Programmed Cell Death Vesicle-mediated Transport Neuron Apoptotic Process Cell Death Death Activation Of MAPKKK Activity Positive Regulation Of P38MAPK Cascade Neuron Death Positive Regulation Of Catalytic Activity Establishment Of Vesicle Localization Positive Regulation Of Cellular Protein Metabolic Process Vesicle Localization Signaling Response To Radiation Single-organism Behavior Cell Communication Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Learning Or Memory Regulation Of P38MAPK Cascade Cognition Regulation Of Signaling Regulation Of Cellular Process Positive Regulation Of Proteolysis Synaptic Vesicle Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Behavior Positive Regulation Of Cell Death Regulation Of Apoptotic Process Establishment Of Organelle Localization Response To Light Stimulus Regulation Of Cell Death Response To Abiotic Stimulus Response To Ionizing Radiation Response To Stress Regulation Of Protein Binding Regulation Of Signal Transduction Positive Regulation Of Transport Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Membrane Permeability Organelle Localization Endoplasmic Reticulum Calcium Ion Homeostasis Synaptic Vesicle Endocytosis Signal Transduction
Tagcloud ?		aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Difference) ?		aurka birc5 c11orf30 ccne1 cdc6 cdh1 cpd devoid emsy esr1 fgfr1 holland ikbkb mapt mathematical meaning med1 microdissection mlpa mrc mtdh multiplex numerical p078 prdm14 qiagen salsa top2a traf4
Tagcloud (Intersection) ?