MYH13 and LSM7

Number of citations of the paper that reports this interaction (PubMedID 15231747)
47

Data Source:
HPRD (two hybrid)

		MYH13	LSM7
Description		myosin heavy chain 13	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Muscle Myosin Complex Myosin Complex Myosin II Complex Myofibril Myosin Filament Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex U6 SnRNP U12-type Spliceosomal Complex Cytosol U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome Spliceosomal Tri-snRNP Complex Lsm2-8 Complex Lsm1-7-Pat1 Complex Ribonucleoprotein Complex
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Calmodulin Binding ATP Binding Actin Filament Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Muscle Contraction Cellular Response To Starvation	MRNA Splicing, Via Spliceosome Nuclear-transcribed MRNA Catabolic Process MRNA Processing RNA Splicing
Pathways			mRNA decay by 5' to 3' exoribonuclease mRNA decay by 5' to 3' exoribonuclease mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Major depressive disorder ( 27777418) Periodontitis (stage III/IV grade C) ( 33745150)	Parkinson's disease ( 28892059)
Interacting Genes		2 interacting genes: LSM7 USP7	24 interacting genes: CEBPA DDIT4L EPHA2 EXOSC6 EXOSC8 LDB1 LSM1 LSM2 LSM3 LSM5 LSM6 LSM8 MYH13 NPY1R PFKM RAB29 RASSF5 SMN1 SNRPD3 SNRPF SYT17 TACC1 TCL1B ZSCAN26
Entrez ID		8735	51690
HPRD ID		04599	06287
Ensembl ID		ENSG00000006788	ENSG00000130332
Uniprot IDs		Q9UKX3	Q9UK45
PDB IDs			3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG 8H6E 8H6J 8H6K 8H6L 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5
Enriched GO Terms of Interacting Partners?		Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Establishment Of Protein Localization To Telomere Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Retrograde Transport, Endosome To Golgi Lsm2-8 Complex Lsm1-7-Pat1 Complex Spliceosomal Tri-snRNP Complex Monoubiquitinated Protein Deubiquitination U6 SnRNP DNA Alkylation Repair Transcription-coupled Nucleotide-excision Repair U6 SnRNA Binding Regulation Of Telomere Capping Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Negative Regulation Of Gluconeogenesis K48-linked Deubiquitinase Activity U2-type Prespliceosome Deubiquitinase Activity U12-type Spliceosomal Complex Negative Regulation Of Gene Expression U4/U6 X U5 Tri-snRNP Complex Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleotide-excision Repair Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of TORC1 Signaling Regulation Of Gluconeogenesis Negative Regulation Of Proteasomal Protein Catabolic Process TORC1 Signaling Cysteine-type Endopeptidase Activity U2-type Precatalytic Spliceosome P53 Binding Negative Regulation Of Autophagy Negative Regulation Of Small Molecule Metabolic Process Cysteine-type Deubiquitinase Activity Autophagosome Organization Protein Deubiquitination Protein Modification By Small Protein Removal Autophagosome Assembly Regulation Of TORC1 Signaling Regulation Of Circadian Rhythm Negative Regulation Of TOR Signaling TOR Signaling Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Protein Catabolic Process Regulation Of Telomere Maintenance Regulation Of Glucose Metabolic Process Nucleic Acid Metabolic Process PML Body Nuclear-transcribed MRNA Catabolic Process	U4/U6 X U5 Tri-snRNP Complex Lsm2-8 Complex U2-type Precatalytic Spliceosome U6 SnRNP RNA Splicing, Via Transesterification Reactions Lsm1-7-Pat1 Complex MRNA Metabolic Process RNA Splicing MRNA Processing Spliceosomal Complex RNA Processing MRNA Splicing, Via Spliceosome RNA Metabolic Process Precatalytic Spliceosome MRNA Catabolic Process Ribonucleoprotein Complex Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Spliceosomal SnRNP Assembly Nucleobase-containing Compound Catabolic Process Nucleic Acid Metabolic Process Small Nuclear Ribonucleoprotein Complex SMN-Sm Protein Complex RNA Binding Catalytic Step 2 Spliceosome P-body PICln-Sm Protein Complex Spliceosomal Complex Assembly U7 SnRNP 7-methylguanosine Cap Hypermethylation U4 SnRNA 3'-end Processing Nucleolar Exosome (RNase Complex) U4 SnRNP Nuclear MRNA Surveillance Methylosome U6 SnRNA Binding Protein-RNA Complex Assembly Cytoplasmic Exosome (RNase Complex) RNA Exonuclease Activity RRNA Catabolic Process Nuclear Exosome (RNase Complex) Exosome (RNase Complex) U1 SnRNP Nucleoplasm U5 SnRNP SnRNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process Macromolecule Catabolic Process U2-type Prespliceosome Assembly U12-type Spliceosomal Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?