ATP6V0A1

Name	ATPase H+ transporting V0 subunit a1
Structure
Interactors	8 interactors: ABLIM2 CLIC1 CYTH2 HRH1 SEH1L SNX4 TTC3 ZNF267
GO Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V0 Domain Cytoplasm Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting V-type ATPase, V0 Domain Melanosome Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Endosomal Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs	Tiludronic acid
GWAS	Asthma ( 32296059 ) Crohn's disease ( 28067908 ) Inflammatory bowel disease ( 28067908 ) Ulcerative colitis ( 28067908 ) Waist-hip index ( 34021172 ) Waist-to-hip ratio adjusted for BMI ( 34021172 )
Entrez ID	535
HPRD ID	01886
Ensembl ID	ENSG00000033627
Uniprot IDs	A0A994J3Z0 A0A994J3Z4 A0A994J3Z9 B7Z2A9 B7Z641 K7EN36 K7ENA1 K7ERA6 Q53ET5 Q53X12 Q93050
PDB IDs	6WLW 6WM2 6WM3 6WM4 7U4T