DGAT1 and CD1A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		DGAT1	CD1A
Description		diacylglycerol O-acyltransferase 1	CD1a molecule
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane Intracellular Membrane-bounded Organelle	Extracellular Space Endosome Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Membrane Raft
	Molecular Function	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding O-acyltransferase Activity Transferase Activity Acyltransferase Activity Identical Protein Binding Retinol O-fatty-acyltransferase Activity	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Retinoid Metabolic Process Lipid Metabolic Process Monoacylglycerol Biosynthetic Process Triglyceride Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Retinol Metabolic Process Diacylglycerol Metabolic Process Glycerolipid Metabolic Process Fatty Acid Homeostasis	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune System Process Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Acyl chain remodeling of DAG and TAG Neutrophil degranulation Triglyceride biosynthesis	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Dupuytren's disease ( 28886342) Fasting glucose ( 34059833)	Change in neurofilament light levels ( 31295725) Dental caries (decayed and filled deciduous teeth) ( 31533690)
Interacting Genes		3 interacting genes: CCR9 CD1A GABRA4	4 interacting genes: B2M DGAT1 KCTD5 UBTD1
Entrez ID		8694	909
HPRD ID		05360	01776
Ensembl ID		ENSG00000185000	ENSG00000158477
Uniprot IDs		O75907	P06126
PDB IDs		6VP0 6VYI 6VZ1 8ESM 8ETM	1ONQ 1XZ0 4X6C 4X6D 4X6E 4X6F 5J1A 6NUX 7KOZ 7KP0 7KP1 7RYM 7RYN 7RYO 7SH4
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Exogenous Lipid Antigen Binding Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Endogenous Lipid Antigen Binding GPI-anchor Transamidase Activity GPI-anchor Transamidase Complex Attachment Of GPI Anchor To Protein GPI Anchored Protein Biosynthesis CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Protein Retention In ER Lumen Lipopeptide Binding GPI Anchor Binding External Side Of Plasma Membrane Benzodiazepine Receptor Activity Gamma-delta T Cell Differentiation Maintenance Of Protein Localization In Endoplasmic Reticulum GABA-A Receptor Activity GABA-A Receptor Complex GABA-gated Chloride Ion Channel Activity Inhibitory Synapse Assembly Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Gamma-delta T Cell Activation Antigen Processing And Presentation Of Endogenous Antigen Gamma-aminobutyric Acid Signaling Pathway Postsynaptic Specialization Membrane GPI Anchor Metabolic Process GPI Anchor Biosynthetic Process Dendrite Membrane Synaptic Transmission, GABAergic Positive Regulation Of T Cell Mediated Cytotoxicity Extracellular Ligand-gated Monoatomic Ion Channel Activity Transmitter-gated Monoatomic Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Cellular Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Protein Homooligomerization Negative Regulation Of Forebrain Neuron Differentiation Regulation Of Forebrain Neuron Differentiation Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Negative Regulation Of Iron Ion Transport Diacylglycerol O-acyltransferase Activity 2-acylglycerol O-acyltransferase Activity Retinol O-fatty-acyltransferase Activity Cellular Response To Nicotine HFE-transferrin Receptor Complex Regulation Of Iron Ion Transport MHC Class I Protein Complex MHC Class I Peptide Loading Complex Cellular Response To Iron Ion Early Endosome Lumen Protein Complex Oligomerization Protein-containing Complex Organization Peptide Antigen Assembly With MHC Class I Protein Complex Protein-containing Complex Assembly Monoacylglycerol Biosynthetic Process Transferrin Transport Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Cellular Senescence Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Identical Protein Binding Fatty Acid Homeostasis Triglyceride Biosynthetic Process MHC Class II Protein Complex Binding T Cell Mediated Cytotoxicity Multicellular Organismal-level Iron Ion Homeostasis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Long-chain Fatty-acyl-CoA Metabolic Process Diacylglycerol Metabolic Process O-acyltransferase Activity Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Cullin Family Protein Binding Protein Refolding Positive Regulation Of T Cell Cytokine Production Antigen Processing And Presentation Of Endogenous Antigen Amyloid Fibril Formation Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Response To Iron Ion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?