DGAT1 and CD1A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DGAT1	CD1A
Gene Name		diacylglycerol O-acyltransferase 1	CD1a molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane
	Molecular Function	2-acylglycerol O-acyltransferase Activity Diacylglycerol O-acyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups Retinol O-fatty-acyltransferase Activity	Protein Binding Beta-2-microglobulin Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Triglyceride Metabolic Process Phospholipid Metabolic Process Triglyceride Biosynthetic Process Lipid Storage Very-low-density Lipoprotein Particle Assembly Long-chain Fatty-acyl-CoA Metabolic Process Acylglycerol Acyl-chain Remodeling Retinol Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Diacylglycerol Metabolic Process Glycerophospholipid Biosynthetic Process Fatty Acid Homeostasis	Immune Response Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Acyl chain remodeling of DAG and TAG Phospholipid metabolism Glycerophospholipid biosynthesis Triglyceride Biosynthesis
Drugs			Antithymocyte globulin
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CD1A GABRA4	4 interactors: B2M DGAT1 KCTD5 UBTD1
Entrez ID		8694	909
HPRD ID		05360	01776
Ensembl ID			ENSG00000158477
Uniprot IDs		O75907	P06126
PDB IDs			1ONQ 1XZ0
Enriched GO Terms of Interacting Partners?		Regulation Of Response To Drug Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Gamma-aminobutyric Acid Signaling Pathway	Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Acylglycerol Acyl-chain Remodeling Very-low-density Lipoprotein Particle Assembly Viral Process Ion Homeostasis Fatty Acid Homeostasis Protein-lipid Complex Assembly Diacylglycerol Metabolic Process Protein Refolding Long-chain Fatty-acyl-CoA Metabolic Process Regulation Of Defense Response To Virus By Virus Retinol Metabolic Process Chemical Homeostasis Lipid Storage Triglyceride Biosynthetic Process Anion Homeostasis Response To Cadmium Ion Retina Homeostasis Regulation Of Plasma Lipoprotein Particle Levels Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Acyl-CoA Metabolic Process T Cell Differentiation In Thymus Homeostatic Process Retinoid Metabolic Process Regulation Of Defense Response To Virus Positive Regulation Of T Cell Mediated Cytotoxicity Diterpenoid Metabolic Process Regulation Of T Cell Mediated Cytotoxicity Triglyceride Metabolic Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Neutral Lipid Metabolic Process Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Lipid Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Iron Ion Homeostasis Isoprenoid Metabolic Process Interferon-gamma-mediated Signaling Pathway Cellular Component Assembly Cellular Response To Interferon-gamma Transition Metal Ion Homeostasis Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Differentiation
Tagcloud ?		abhd5 agpat2 anomaly atgl cgi ctgm diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated	absent allograft antigen biopsies capillaries colocalization controversial dc dcs demonstrates dendritic dr fascin hla infiltrates interstitium kidney lymphoid mhc migrate p55 passenger rare rejection relied s100 selectively thought viii
Tagcloud (Difference) ?		abhd5 agpat2 anomaly atgl cgi ctgm diverge enteropathy gk glycerol gpd1 hsl ichthyosis inborn jordan lipe lipodystrophy loosing lpin1 lpin2 majeed nlsd perilipin pnpla2 pseudohypertriglyceridemia rhabdomyolysis steatosis tgs vacuolated	absent allograft antigen biopsies capillaries colocalization controversial dc dcs demonstrates dendritic dr fascin hla infiltrates interstitium kidney lymphoid mhc migrate p55 passenger rare rejection relied s100 selectively thought viii
Tagcloud (Intersection) ?