CD1A

Gene Name		CD1a molecule
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane
	Molecular Function	Protein Binding Beta-2-microglobulin Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Immune Response Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways
Drugs		Antithymocyte globulin
Diseases
GWAS
Protein-protein Interactions		4 interactors: B2M DGAT1 KCTD5 UBTD1
Entrez ID		909
HPRD ID		01776
Ensembl ID		ENSG00000158477
Uniprot IDs		P06126
PDB IDs		1ONQ 1XZ0
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Acylglycerol Acyl-chain Remodeling Very-low-density Lipoprotein Particle Assembly Viral Process Ion Homeostasis Fatty Acid Homeostasis Protein-lipid Complex Assembly Diacylglycerol Metabolic Process Protein Refolding Long-chain Fatty-acyl-CoA Metabolic Process Regulation Of Defense Response To Virus By Virus Retinol Metabolic Process Chemical Homeostasis Lipid Storage Triglyceride Biosynthetic Process Anion Homeostasis Response To Cadmium Ion Retina Homeostasis Regulation Of Plasma Lipoprotein Particle Levels Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Acyl-CoA Metabolic Process T Cell Differentiation In Thymus Homeostatic Process Retinoid Metabolic Process Regulation Of Defense Response To Virus Positive Regulation Of T Cell Mediated Cytotoxicity Diterpenoid Metabolic Process Regulation Of T Cell Mediated Cytotoxicity Triglyceride Metabolic Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Neutral Lipid Metabolic Process Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Lipid Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Iron Ion Homeostasis Isoprenoid Metabolic Process Interferon-gamma-mediated Signaling Pathway Cellular Component Assembly Cellular Response To Interferon-gamma Transition Metal Ion Homeostasis Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Differentiation
Tagcloud ?		absent allograft antigen biopsies capillaries colocalization controversial dc dcs demonstrates dendritic dr fascin hla infiltrates interstitium kidney lymphoid mhc migrate p55 passenger rare rejection relied s100 selectively thought viii