CD1A and UBTD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CD1A	UBTD1
Gene Name		CD1a molecule	ubiquitin domain containing 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Endosome Membrane
	Molecular Function	Protein Binding Beta-2-microglobulin Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding
	Biological Process	Immune Response Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways
Drugs		Antithymocyte globulin
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: B2M DGAT1 KCTD5 UBTD1	13 interactors: BCOR CD1A FZD5 KIAA2026 MID1 MID2 MRFAP1L1 PFKM RANBP2 RNF10 TEAD1 TRIM39 UBE2D4
Entrez ID		909	80019
HPRD ID		01776	08568
Ensembl ID		ENSG00000158477	ENSG00000165886
Uniprot IDs		P06126	Q9HAC8
PDB IDs		1ONQ 1XZ0
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Acylglycerol Acyl-chain Remodeling Very-low-density Lipoprotein Particle Assembly Viral Process Ion Homeostasis Fatty Acid Homeostasis Protein-lipid Complex Assembly Diacylglycerol Metabolic Process Protein Refolding Long-chain Fatty-acyl-CoA Metabolic Process Regulation Of Defense Response To Virus By Virus Retinol Metabolic Process Chemical Homeostasis Lipid Storage Triglyceride Biosynthetic Process Anion Homeostasis Response To Cadmium Ion Retina Homeostasis Regulation Of Plasma Lipoprotein Particle Levels Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Acyl-CoA Metabolic Process T Cell Differentiation In Thymus Homeostatic Process Retinoid Metabolic Process Regulation Of Defense Response To Virus Positive Regulation Of T Cell Mediated Cytotoxicity Diterpenoid Metabolic Process Regulation Of T Cell Mediated Cytotoxicity Triglyceride Metabolic Process Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of T Cell Mediated Immunity Neutral Lipid Metabolic Process Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Lipid Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Iron Ion Homeostasis Isoprenoid Metabolic Process Interferon-gamma-mediated Signaling Pathway Cellular Component Assembly Cellular Response To Interferon-gamma Transition Metal Ion Homeostasis Positive Regulation Of Adaptive Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I T Cell Differentiation	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein Localization To Microtubule Protein Localization To Cytoskeleton Negative Regulation Of Histone H3-K36 Methylation Negative Regulation Of Tooth Mineralization Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Pattern Specification Process Axis Specification Depurination Regulation Of Chorionic Trophoblast Cell Proliferation Spemann Organizer Formation Protein Localization To Organelle Cellular Protein Modification Process Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Signal Transduction Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Specification Of Axis Polarity Negative Regulation Of Odontogenesis Negative Regulation Of Glucokinase Activity Positive Regulation Of Stem Cell Maintenance DNA Dealkylation Involved In DNA Repair Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Histone H3-K4 Methylation Base-excision Repair, AP Site Formation Chorionic Trophoblast Cell Differentiation Protein K6-linked Ubiquitination Glucose Homeostasis Chorion Development Pathogenesis Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Myelination Regulation Of Tight Junction Assembly Negative Regulation Of Glial Cell Proliferation Post-embryonic Camera-type Eye Development Fructose 6-phosphate Metabolic Process Branching Involved In Labyrinthine Layer Morphogenesis Positive Regulation Of Intracellular Signal Transduction Histone H2A Monoubiquitination Regulation Of Metabolic Process Lateral Mesoderm Development Cardiovascular System Development Negative Regulation Of Viral Release From Host Cell Histone H2A Ubiquitination
Tagcloud ?		absent allograft antigen biopsies capillaries colocalization controversial dc dcs demonstrates dendritic dr fascin hla infiltrates interstitium kidney lymphoid mhc migrate p55 passenger rare rejection relied s100 selectively thought viii	attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Difference) ?		absent allograft antigen biopsies capillaries colocalization controversial dc dcs demonstrates dendritic dr fascin hla infiltrates interstitium kidney lymphoid mhc migrate p55 passenger rare rejection relied s100 selectively thought viii	attenuation barrier besides britain constitutes copyright correlates creates damageing depend depends feedback great impacts ireland john ltd mdm2 mutually passageing premature senescence serial society sons transformed tumourigenesis wiley worse
Tagcloud (Intersection) ?