CD1A and UBTD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CD1A	UBTD1
Description		CD1a molecule	ubiquitin domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endosome Plasma Membrane External Side Of Plasma Membrane Endosome Membrane Membrane Membrane Raft
	Molecular Function	Protein Binding Endogenous Lipid Antigen Binding Exogenous Lipid Antigen Binding Lipopeptide Binding	Protein Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response Immune System Process Immune Response Antigen Processing And Presentation, Endogenous Lipid Antigen Via MHC Class Ib Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		Antithymocyte immunoglobulin (rabbit)
Diseases
GWAS		Change in neurofilament light levels ( 31295725) Dental caries (decayed and filled deciduous teeth) ( 31533690)	Obesity-related traits ( 23251661) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		4 interacting genes: B2M DGAT1 KCTD5 UBTD1	20 interacting genes: BCOR BRD10 CD1A FZD5 MID1 MID2 MRFAP1 MRFAP1L1 PFKM RANBP2 RNF10 RNF5 TEAD1 TP53BP2 TRAF6 TRIM39 TRIM50 UBE2D1 UBE2D4 WWP2
Entrez ID		909	80019
HPRD ID		01776	08568
Ensembl ID		ENSG00000158477	ENSG00000165886
Uniprot IDs		P06126	Q9HAC8
PDB IDs		1ONQ 1XZ0 4X6C 4X6D 4X6E 4X6F 5J1A 6NUX 7KOZ 7KP0 7KP1 7RYM 7RYN 7RYO 7SH4
Enriched GO Terms of Interacting Partners?		Cellular Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class Ib Protein Homooligomerization Negative Regulation Of Forebrain Neuron Differentiation Regulation Of Forebrain Neuron Differentiation Response To Iron(III) Ion Antigen Processing And Presentation Of Exogenous Protein Antigen Via MHC Class Ib, TAP-dependent Negative Regulation Of Iron Ion Transport Diacylglycerol O-acyltransferase Activity 2-acylglycerol O-acyltransferase Activity Retinol O-fatty-acyltransferase Activity Cellular Response To Nicotine HFE-transferrin Receptor Complex Regulation Of Iron Ion Transport MHC Class I Protein Complex MHC Class I Peptide Loading Complex Cellular Response To Iron Ion Early Endosome Lumen Protein Complex Oligomerization Protein-containing Complex Organization Peptide Antigen Assembly With MHC Class I Protein Complex Protein-containing Complex Assembly Monoacylglycerol Biosynthetic Process Transferrin Transport Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Cellular Senescence Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Identical Protein Binding Fatty Acid Homeostasis Triglyceride Biosynthetic Process MHC Class II Protein Complex Binding T Cell Mediated Cytotoxicity Multicellular Organismal-level Iron Ion Homeostasis Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Long-chain Fatty-acyl-CoA Metabolic Process Diacylglycerol Metabolic Process O-acyltransferase Activity Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Cullin Family Protein Binding Protein Refolding Positive Regulation Of T Cell Cytokine Production Antigen Processing And Presentation Of Endogenous Antigen Amyloid Fibril Formation Positive Regulation Of T Cell Mediated Cytotoxicity Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Response To Iron Ion Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I	Ubiquitin Protein Ligase Activity Protein Modification By Small Protein Conjugation Transferase Activity Post-translational Protein Modification Protein Ubiquitination Ubiquitin-protein Transferase Activity Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Modification Process Positive Regulation Of T Cell Mediated Immunity Identical Protein Binding Protein Autoubiquitination Protein Localization To Microtubule Regulation Of T Cell Mediated Immunity Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Positive Regulation Of T Cell Cytokine Production Ubiquitin Conjugating Enzyme Activity Zinc Ion Binding Phosphoprotein Binding Macromolecule Catabolic Process Proteolysis Involved In Protein Catabolic Process Regulation Of T Cell Cytokine Production Phosphofructokinase Activity Glycolysis From Storage Polysaccharide Through Glucose-1-phosphate Negative Regulation Of Tooth Mineralization BCOR Complex Antigen Processing And Presentation Of Exogenous Antigen Regulation Of Lymphocyte Mediated Immunity Protein Localization To Cytoskeleton Toll-like Receptor Signaling Pathway Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Adaptive Immune Response Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Proteasomal Protein Catabolic Process Positive Regulation Of Transcription By RNA Polymerase II Cytoplasmic Periphery Of The Nuclear Pore Complex
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