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GALNT4 and MUC1
Number of citations of the paper that reports this interaction (PMID
12754287
)
8
Data Source:
BioGRID
(enzymatic study)
GALNT4
MUC1
Gene Name
polypeptide N-acetylgalactosaminyltransferase 4
mucin 1, cell surface associated
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Golgi Apparatus
Integral Component Of Membrane
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Nuclear Chromatin
Extracellular Space
Cytoplasm
Golgi Lumen
Integral Component Of Plasma Membrane
Cell Surface
Apical Plasma Membrane
Vesicle
Extracellular Vesicular Exosome
Molecular Function
Polypeptide N-acetylgalactosaminyltransferase Activity
Carbohydrate Binding
Metal Ion Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
P53 Binding
Transcription Cofactor Activity
Protein Binding
Biological Process
Carbohydrate Metabolic Process
Protein O-linked Glycosylation
O-glycan Processing
Post-translational Protein Modification
Cellular Protein Metabolic Process
Protein O-linked Glycosylation
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of Transcription By Competitive Promoter Binding
O-glycan Processing
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Post-translational Protein Modification
Cellular Protein Metabolic Process
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways
Post-translational protein modification
O-linked glycosylation of mucins
O-linked glycosylation
Post-translational protein modification
Termination of O-glycan biosynthesis
O-linked glycosylation of mucins
O-linked glycosylation
Drugs
Diseases
GWAS
Crohn's disease (
21102463
)
Magnesium levels (
20700443
)
Protein-Protein Interactions
2 interactors:
MUC1
SELPLG
29 interactors:
ABL1
APC
CTNNB1
CTNND1
EGFR
ERBB2
ERBB3
ERBB4
ESR1
GALNT1
GALNT10
GALNT12
GALNT15
GALNT2
GALNT4
GRB2
GSK3B
JUP
LCK
LYN
NUP62
OSGEP
PPARG
PRKCD
SIGLEC1
SOS1
SRC
TP53
ZAP70
Entrez ID
8693
4582
HPRD ID
09152
01152
Ensembl ID
ENSG00000257594
ENSG00000185499
Uniprot IDs
Q8N4A0
A5YRU5
A5YRU7
A5YRU8
A5YRV0
A5YRV2
A6ZID6
A6ZID7
A6ZIE0
A6ZIE2
A6ZIE4
A6ZIE5
A6ZIE6
A6ZIF0
B1AVQ5
B1AVQ7
B6ECB3
P15941
Q7Z538
Q7Z549
Q7Z551
PDB IDs
1SM3
2ACM
2FO4
Enriched GO Terms of Interacting Partners
?
Leukocyte Adhesive Activation
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Transcription By Competitive Promoter Binding
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
DNA Damage Response, Signal Transduction Resulting In Transcription
Leukocyte Tethering Or Rolling
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of Histone H4 Acetylation
Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Positive Regulation Of Histone Acetylation
Negative Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Peptidyl-lysine Acetylation
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Protein Acetylation
Cellular Response To Interleukin-6
Cellular Extravasation
Response To Interleukin-6
Regulation Of Signal Transduction By P53 Class Mediator
O-glycan Processing
Regulation Of Histone Acetylation
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Histone Modification
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
DNA Damage Response, Signal Transduction By P53 Class Mediator
Protein O-linked Glycosylation
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Cycle Arrest
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Signal Transduction By P53 Class Mediator
Regulation Of Histone Modification
Regulation Of Response To DNA Damage Stimulus
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of Mitotic Cell Cycle Phase Transition
DNA Damage Checkpoint
Regulation Of Intrinsic Apoptotic Signaling Pathway
Mitotic Cell Cycle Checkpoint
Positive Regulation Of Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Fc Receptor Signaling Pathway
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Signal Transduction
Immune Response-regulating Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Innate Immune Response
Cellular Response To Fibroblast Growth Factor Stimulus
Regulation Of Signaling
Response To Fibroblast Growth Factor
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Intracellular Signal Transduction
Neurotrophin Signaling Pathway
Regulation Of Cell Death
Cellular Response To Organic Substance
Immune Response
Regulation Of Immune System Process
Negative Regulation Of Signal Transduction
Regulation Of Immune Response
Defense Response
Cell Surface Receptor Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Negative Regulation Of Signaling
Regulation Of Cell Proliferation
Cellular Response To Growth Factor Stimulus
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Response To Growth Factor
Immune System Process
Regulation Of MAPK Cascade
Positive Regulation Of Cell Death
Regulation Of Cell Adhesion
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Phosphorylation
Cell Migration
Fc-epsilon Receptor Signaling Pathway
Cell Activation
Single Organismal Cell-cell Adhesion
Cell Motility
Peptidyl-amino Acid Modification
Regulation Of Phosphorus Metabolic Process
O-glycan Processing
Response To Organic Substance
Positive Regulation Of Protein Metabolic Process
Locomotion
Tagcloud
?
antigens
apomucin
basal
carbohydrate
carcinomas
eyelid
galnac
gland
glycoprotein
granuloma
immunohistochemically
keratosis
mucin
neuac
nevus
organs
papilloma
pseudotumors
rarely
sebaceous
seborrheic
ser
sialosyl
squamous
stn
thr
tn
verruca
vulgaris
Tagcloud (Difference)
?
antigens
apomucin
basal
carbohydrate
carcinomas
eyelid
galnac
gland
glycoprotein
granuloma
immunohistochemically
keratosis
mucin
neuac
nevus
organs
papilloma
pseudotumors
rarely
sebaceous
seborrheic
ser
sialosyl
squamous
stn
thr
tn
verruca
vulgaris
Tagcloud (Intersection)
?