GALNT4 and SELPLG

Number of citations of the paper that reports this interaction (PMID 9804815)
26

Data Source:
HPRD (in vitro)

		GALNT4	SELPLG
Gene Name		polypeptide N-acetylgalactosaminyltransferase 4	selectin P ligand
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Polypeptide N-acetylgalactosaminyltransferase Activity Carbohydrate Binding Metal Ion Binding	Receptor Binding Protein Binding
	Biological Process	Carbohydrate Metabolic Process Protein O-linked Glycosylation O-glycan Processing Post-translational Protein Modification Cellular Protein Metabolic Process	Cell Adhesion Blood Coagulation Leukocyte Migration Leukocyte Tethering Or Rolling Leukocyte Adhesive Activation Cellular Response To Interleukin-6
Pathways		Post-translational protein modification O-linked glycosylation of mucins O-linked glycosylation	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			Conduct disorder (symptom count) ( 20585324)
Protein-Protein Interactions		2 interactors: MUC1 SELPLG	13 interactors: BACE1 CTSG GALNT4 MAGEA1 MSN SELE SELL SELP SYK TNIP1 TPST1 TPST2 VCAN
Entrez ID		8693	6404
HPRD ID		09152	02845
Ensembl ID		ENSG00000257594	ENSG00000110876
Uniprot IDs		Q8N4A0	Q14242
PDB IDs			1G1S
Enriched GO Terms of Interacting Partners?		Leukocyte Adhesive Activation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Transcription By Competitive Promoter Binding DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Leukocyte Tethering Or Rolling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Histone H4 Acetylation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Histone Acetylation Negative Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Protein Acetylation Cellular Response To Interleukin-6 Cellular Extravasation Response To Interleukin-6 Regulation Of Signal Transduction By P53 Class Mediator O-glycan Processing Regulation Of Histone Acetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Histone Modification Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Protein O-linked Glycosylation Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cell Cycle Arrest Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Regulation Of Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Checkpoint	Leukocyte Migration Peptidyl-tyrosine Sulfation Leukocyte Cell-cell Adhesion Cell Adhesion Regulation Of Immune System Process Inflammatory Response Cell Migration Protein Sulfation Cell Motility Single Organismal Cell-cell Adhesion Leukocyte Tethering Or Rolling Sulfation Locomotion Regulation Of Leukocyte Migration Defense Response Immune System Process Blood Coagulation Hemostasis Movement Of Cell Or Subcellular Component Positive Regulation Of Immune System Process Response To Bacterium Cellular Extravasation Regulation Of Platelet Activation Defense Response To Bacterium Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Regulation Of Body Fluid Levels Response To Fungus Wound Healing Response To Wounding Response To Other Organism Response To Biotic Stimulus Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Lipopolysaccharide Platelet Degranulation Response To Molecule Of Bacterial Origin Sulfur Compound Metabolic Process Regulation Of Immune Response Response To Stress Positive Regulation Of Leukocyte Migration Glycoprotein Biosynthetic Process Cellular Response To Molecule Of Fungal Origin Neutrophil Mediated Killing Of Gram-positive Bacterium Beta Selection Selenium Compound Metabolic Process Positive Regulation Of Interleukin-3 Biosynthetic Process Regulation Of Blood Coagulation Glycoprotein Metabolic Process Serotonin Secretion By Platelet Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Biosynthetic Process Prevention Of Polyspermy
Tagcloud ?			aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations
Tagcloud (Difference) ?			aggregates allele angioplasty atherothrombosis carrier carriers depended glycoprotein ile62 inducible irrespective leukocyte lpa monocyte mpa npa pivotal platelet pp pro715 psgl selectin sp stenting stronger thrombin trap variations
Tagcloud (Intersection) ?