BECN1 and ATG3

Number of citations of the paper that reports this interaction (PMID 24186333)
0

Data Source:
BioGRID (pull down)

		BECN1	ATG3
Gene Name		beclin 1, autophagy related	autophagy related 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Pre-autophagosomal Structure Nucleus Trans-Golgi Network Cytoplasmic Membrane-bounded Vesicle Extrinsic Component Of Membrane Dendrite Phosphatidylinositol 3-kinase Complex, Class III, Type I Phosphatidylinositol 3-kinase Complex, Class III, Type II Phagocytic Vesicle	Cytoplasmic Ubiquitin Ligase Complex Cytosol
	Molecular Function	Protein Binding	Protein Binding Atg8 Ligase Activity Atg12 Transferase Activity Ubiquitin-like Protein Transferase Activity Enzyme Binding
	Biological Process	Autophagic Vacuole Assembly Cytokinesis Response To Hypoxia Cellular Defense Response Cellular Response To Nitrogen Starvation Lysosome Organization Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Viral Process Positive Regulation Of Macroautophagy CVT Pathway Response To Vitamin E Response To Drug Negative Regulation Of Apoptotic Process Nucleophagy Late Endosome To Vacuole Transport Neuron Development Beta-amyloid Metabolic Process Regulation Of Catalytic Activity Defense Response To Virus Cellular Response To Aluminum Ion Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Mitochondrion Degradation	Autophagic Vacuole Assembly Mitochondrion Degradation Cellular Protein Modification Process Protein Targeting To Membrane Protein Ubiquitination Mitochondrial Fragmentation Involved In Apoptotic Process Nucleophagy Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: AMBRA1 ATG14 ATG3 BCL2 BCL2L1 CASP3 CDKN2A GFI1B GOPC ITCH NEDD4 PIK3R4 TRAF6 WASH1 XPO1	8 interactors: ATG12 ATG5 ATG7 BECN1 GABARAP GABARAPL2 MAP1LC3A MAP1LC3B
Entrez ID		8678	64422
HPRD ID		05087	10654
Ensembl ID		ENSG00000126581	ENSG00000144848
Uniprot IDs		E7EV84 Q14457	Q9NT62
PDB IDs		2P1L 2PON 3DVU 4DDP
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Apoptotic Mitochondrial Changes Protein K63-linked Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Polyubiquitination Cellular Response To Stress Intracellular Transport Intracellular Receptor Signaling Pathway Regulation Of Execution Phase Of Apoptosis Regulation Of Autophagy Regulation Of Organelle Organization Release Of Cytochrome C From Mitochondria Establishment Of Localization In Cell Protein Ubiquitination Apoptotic Process Negative Regulation Of Cellular Metabolic Process Programmed Cell Death Protein Modification By Small Protein Conjugation Regulation Of Cellular Localization Cellular Response To Starvation Cell Death Death Regulation Of T Cell Proliferation Regulation Of Establishment Of Protein Localization Organelle Organization Autophagy Mitochondrion Organization Regulation Of Lymphocyte Activation Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Localization Cellular Response To Nutrient Levels Response To Starvation Regulation Of Protein Localization Regulation Of Intracellular Transport Neuron Apoptotic Process Macroautophagy Response To Stress Regulation Of B Cell Proliferation Regulation Of Cell Activation Neuron Death Cellular Response To Extracellular Stimulus Negative Regulation Of T Cell Proliferation Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Lymphocyte Proliferation Negative Regulation Of Mononuclear Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Leukocyte Proliferation	Nucleophagy Cellular Response To Nitrogen Starvation Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Cellular Response To Starvation Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Extracellular Stimulus Vacuole Organization Response To Nutrient Levels Response To Extracellular Stimulus Mitochondrion Organization Organelle Assembly Membrane Fusion Cellular Response To Stress Catabolic Process Response To External Stimulus C-terminal Protein Lipidation Negative Regulation Of Histone H4-K16 Acetylation Organelle Organization Cellular Component Assembly Response To Stress Negative Regulation Of Histone H4 Acetylation Negative Stranded Viral RNA Replication Membrane Organization Protein Lipidation Regulation Of Histone H4 Acetylation Positive Regulation Of Mucus Secretion Lipoprotein Biosynthetic Process Positive Regulation Of Macroautophagy Regulation Of Mucus Secretion Negative Regulation Of Histone Acetylation Cell Communication Negative Regulation Of Peptidyl-lysine Acetylation Negative Regulation Of Protein Acetylation Viral Genome Replication Lipoprotein Metabolic Process Post-translational Protein Modification Cellular Response To Stimulus Positive Regulation Of Autophagy Regulation Of Histone Acetylation Negative Regulation Of Type I Interferon Production Cardiac Muscle Cell Development Response To Stimulus Cellular Response To Aluminum Ion Negative Regulation Of Chromosome Organization Regulation Of Type I Interferon Production
Tagcloud ?		antiretroviral antiviral ascribed assemble atg8 autophagic autophagy cargo constitutes defines destruction establishes exemplified explains hitherto machinery nucleate platforms preparation recognizes regulators reminiscent restriction trim trim5 trim5alpha trims tripartite ulk1	alkaloids anticancer araguspongine araguspongines atg16l atg7 autophagic autophagy bt cascade docking dysregulations inositol kinases lc3a lyte macrocyclic marine met overexpressing oxaquinolizidine remarkably silico sponge trisphosphate tyrosine vacuole xestospongia xestospongin
Tagcloud (Difference) ?		antiretroviral antiviral ascribed assemble atg8 cargo constitutes defines destruction establishes exemplified explains hitherto machinery nucleate platforms preparation recognizes regulators reminiscent restriction trim trim5 trim5alpha trims tripartite ulk1	alkaloids anticancer araguspongine araguspongines atg16l atg7 bt cascade docking dysregulations inositol kinases lc3a lyte macrocyclic marine met overexpressing oxaquinolizidine remarkably silico sponge trisphosphate tyrosine vacuole xestospongia xestospongin
Tagcloud (Intersection) ?		autophagic autophagy