WDR37 and EIF4G3

Number of citations of the paper that reports this interaction (PubMedID 34642815)
38

Data Source:
BioGRID (two hybrid)

		WDR37	EIF4G3
Description		WD repeat domain 37	eukaryotic translation initiation factor 4 gamma 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function	Protein Binding	RNA Cap Binding RNA Binding MRNA Binding Translation Initiation Factor Activity Protein Binding Translation Factor Activity, RNA Binding
	Biological Process	Lymphocyte Homeostasis Corpus Callosum Development	Translation Translational Initiation Regulation Of Translation Regulation Of Translational Initiation Spermatid Development Negative Regulation Of Autophagy Positive Regulation Of Translation
Pathways			ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146 26831199) Estimated glomerular filtration rate ( 30604766 31015462) Glomerular filtration rate (creatinine) ( 26831199 28452372) Glomerular filtration rate in non diabetics (creatinine) ( 26831199) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Chronotype ( 30696823) Cognitive decline rate in late mild cognitive impairment ( 26252872) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) General risk tolerance (MTAG) ( 30643258) Mean spheric corpuscular volume ( 32888494) Morning person ( 30696823) Postoperative acute renal failure after cardiac surgery ( 30678657) Red blood cell count ( 32888494) Social science traits (pleiotropy) (HIPO component 1) ( 30289880) Superior frontal gyrus grey matter volume ( 25335168)
Interacting Genes		5 interacting genes: COL12A1 EIF4G3 EWSR1 MEOX2 TRIP11	17 interacting genes: CAMK1 CTNND1 DDX19B EIF4A1 EIF4E HSPB1 LIG4 LSM3 MKNK1 PABPC1 PCNT PSMB6 RNF10 TRIM25 VAV2 VPS25 WDR37
Entrez ID		22884	8672
HPRD ID		15668	06802
Ensembl ID		ENSG00000047056	ENSG00000075151
Uniprot IDs		Q9Y2I8	A0A0A0MSA7 A0A804HJV5 A0A8I5QJH9 A0A8J9G7U8 B4DXR2 O43432 Q59GJ0
PDB IDs			1HU3
Enriched GO Terms of Interacting Partners?			Cytoplasmic Stress Granule Nucleus Cytoplasm RNA Cap Binding Eukaryotic Translation Initiation Factor 4F Complex Cytosol Calcium/calmodulin-dependent Protein Kinase Activity Extracellular Exosome RNA Binding Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Translation
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