DDX3Y and MIR25

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		DDX3Y	MIR25
Description		DEAD-box helicase 3 Y-linked	microRNA 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane P Granule	Extracellular Space RISC Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Gamete Generation Negative Regulation Of Gene Expression Cell Differentiation	MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways
Drugs
Diseases
GWAS		Autism ( 32996047)
Interacting Genes		21 interacting genes: MIR106A MIR106B MIR107 MIR128-2 MIR143 MIR15B MIR18B MIR19B2 MIR20A MIR25 MIR31 MIR34A MIR363 MIR7-1 MIR7-2 MIR98 MIRLET7B MIRLET7D MIRLET7F1 MIRLET7G SHBG	100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3
Entrez ID		8653	407014
HPRD ID		02452
Ensembl ID		ENSG00000067048	ENSG00000207547
Uniprot IDs		O15523
PDB IDs
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cytokine Production Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Space Negative Regulation Of Developmental Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Angiogenesis Negative Regulation Of Multicellular Organismal Process Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway MRNA Destabilization Regulation Of Endothelial Cell Migration RNA Destabilization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Multicellular Organismal Development Negative Regulation Of Glycoprotein Biosynthetic Process Regulation Of Translation Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Spliceosomal Complex Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Negative Regulation Of Metabolic Process P-body
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