DDX3Y and MIR107

Number of citations: 0 (PubMedID 28431233)
Data Source: BioGRID (unspecified method)

		DDX3Y	MIR107
Name		DEAD-box helicase 3 Y-linked	microRNA 107
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane P Granule	Extracellular Space RISC Complex Neuronal Cell Body Extracellular Vesicle
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity	MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	Gamete Generation Negative Regulation Of Gene Expression Cell Differentiation	Cellular Response To Insulin Stimulus MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Gluconeogenesis Negative Regulation Of D-glucose Import Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Necroptotic Process Cellular Response To Hydrogen Peroxide Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production
GWAS		Autism ( 32996047 )	No GWAS studies recorded
Novel Interactors		2 novel interactors: CCR1 NPHP3	None recorded
Interacting Genes		21 interacting genes: MIR106A MIR106B MIR107 MIR128-2 MIR143 MIR15B MIR18B MIR19B2 MIR20A MIR25 MIR31 MIR34A MIR363 MIR7-1 MIR7-2 MIR98 MIRLET7B MIRLET7D MIRLET7F1 MIRLET7G SHBG	83 interacting genes: AIMP1 AIMP2 AQR C1QBP CDC5L CELF1 CPSF1 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 NUFIP2 P3H1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM17 RTCB SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3 ZNF346
Entrez ID		8653	406901
HPRD ID		02452	Not available
Ensembl ID		ENSG00000067048	ENSG00000198997
Uniprot IDs		O15523	Not available
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cytokine Production Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Space Negative Regulation Of Developmental Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Angiogenesis Negative Regulation Of Multicellular Organismal Process Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway MRNA Destabilization Regulation Of Endothelial Cell Migration RNA Destabilization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Multicellular Organismal Development Negative Regulation Of Glycoprotein Biosynthetic Process Regulation Of Translation Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Binding Spliceosomal Complex Regulation Of RNA Splicing Nucleoplasm Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Catalytic Step 2 Spliceosome Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Negative Regulation Of RNA Catabolic Process MRNA 3'-UTR Binding Regulation Of RNA Stability MiRNA Binding Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability MRNA Stabilization Regulation Of Translation TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation U2 SnRNP Positive Regulation Of Gene Expression Regulation Of Gene Expression Negative Regulation Of Translation Positive Regulation Of Cytoplasmic Translation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process CRD-mediated MRNA Stabilization Positive Regulation Of Biosynthetic Process