MIR25 and NUDT21

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR25	NUDT21
Description		microRNA 25	nudix hydrolase 21
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space RISC Complex	Nucleus Nucleoplasm Cytoplasm Centrosome MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Nuclear Body Centriolar Satellite Paraspeckles
	Molecular Function	MRNA Base-pairing Post-transcriptional Repressor Activity	Chromatin Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress	MRNA Processing Post-transcriptional Regulation Of Gene Expression Cell Differentiation MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization MRNA Alternative Polyadenylation Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation
Pathways			mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes		100 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF6 CPSF7 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PATL1 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM17 RBM4 RBM45 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM56 TRIM71 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3	119 interacting genes: A2M ATXN1 CARM1 CDC42 CEBPA CEP126 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G ESR1 EXOSC6 F13A1 FAM90A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIFAP3 KRT75 MASP1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR205 MIR206 MIR20A MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-2 MIR9-2 MIR92A1 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYL6 NEDD4 NGEF NIF3L1 NTAQ1 POLR2C PSMF1 PSPC1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 S100PBP SEM1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP SNRNP70 SPAG8 SRPK1 TCERG1 TEPSIN TLE1 TRA2A TRIM23 TRIM27 WWOX ZNF655
Entrez ID		407014	11051
HPRD ID			05400
Ensembl ID		ENSG00000207547	ENSG00000167005
Uniprot IDs			O43809
PDB IDs			2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T 5R4P 5R4Q 5R4R 5R4S 5R4T 5R4U 5R64 5R65 5R66 5R67
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing MRNA Processing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Nucleus RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Nucleoplasm Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Spliceosomal Complex Ribonucleoprotein Complex Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Regulation Of Translation MiRNA Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Regulation Of MRNA Stability Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Catabolic Process Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Metabolic Process TRNA Aminoacylation Ligase Activity MRNA Stabilization Negative Regulation Of Metabolic Process P-body	MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Blood Vessel Endothelial Cell Migration MRNA Destabilization Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Regulation Of Macromolecule Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Negative Regulation Of Developmental Process Negative Regulation Of Sprouting Angiogenesis Regulation Of Metabolic Process Positive Regulation Of Connective Tissue Replacement Regulation Of Translation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Signal Transduction Regulation Of Sprouting Angiogenesis Negative Regulation Of Protein Metabolic Process
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