DDX3Y

Name	DEAD-box helicase 3 Y-linked
Structure	No pdb structure
Novel Interactors	2 novel interactors: CCR1 NPHP3
Interactors	21 interactors: MIR106A MIR106B MIR107 MIR128-2 MIR143 MIR15B MIR18B MIR19B2 MIR20A MIR25 MIR31 MIR34A MIR363 MIR7-1 MIR7-2 MIR98 MIRLET7B MIRLET7D MIRLET7F1 MIRLET7G SHBG
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane P Granule
	Molecular Function	Nucleotide Binding Nucleic Acid Binding DNA Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Gamete Generation Negative Regulation Of Gene Expression Cell Differentiation
GWAS	Autism ( 32996047 )
Entrez ID	8653
HPRD ID	02452
Ensembl ID	ENSG00000067048
Uniprot IDs	O15523
PDB IDs	Not available
GO Terms Enriched among Interactors ?	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cytokine Production Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Extracellular Space Negative Regulation Of Developmental Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Angiogenesis Negative Regulation Of Multicellular Organismal Process Regulation Of Vasculature Development Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Macromolecule Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway MRNA Destabilization Regulation Of Endothelial Cell Migration RNA Destabilization Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Metabolic Process Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Multicellular Organismal Process Negative Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Multicellular Organismal Development Negative Regulation Of Glycoprotein Biosynthetic Process Regulation Of Translation Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development