JRK and UTP14C

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		JRK	UTP14C
Name		Jrk helix-turn-helix protein	UTP14C small subunit processome component
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ribonucleoprotein Complex	Nucleus Nucleolus Cytosol Small-subunit Processome
	Molecular Function	Nucleic Acid Binding DNA Binding MRNA Binding Protein Binding	Protein Binding
	Biological Process	Positive Regulation Of Canonical Wnt Signaling Pathway	RRNA Processing Spermatogenesis Cell Differentiation Ribosome Biogenesis Meiotic Cell Cycle
Pathways		None	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
GWAS		Urinary tract infection frequency ( 28928442 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: LY6E	1 novel interactors: NUDT15
Interacting Genes		36 interacting genes: ALAS1 BYSL CATSPERT CCDC136 CCDC57 CDC37 CNKSR3 FAM161A FBXO17 GOLGA6L9 HSF2BP IFRD2 KDM1A KPNA6 LDOC1 LGALS14 MTUS2 PDZD4 PICK1 PRICKLE1 TFIP11 TPM4 TRIM23 TRIM41 TRIP10 TSGA10 TXK USP2 UTP14C ZBTB8A ZNF343 ZNF417 ZNF620 ZNF629 ZNF655 ZRANB1	33 interacting genes: ALAS1 BICD2 C8orf34 CARD10 CCDC57 CEP70 GCC1 GOLGA2 GOLGA6A HOOK1 HOOK2 JRK KANK2 KRT34 KRT40 LZTS2 MCC MEOX2 MTUS2 NAB2 PDE4DIP PIBF1 PRICKLE1 RABEP1 RINT1 RNF10 TEX11 TRAF1 TRAF2 TRIM27 TRIM54 TXLNA USP7
Entrez ID		8629	9724
HPRD ID		04442	12346
Ensembl ID		ENSG00000234616	ENSG00000253797
Uniprot IDs		O75564	Q5TAP6
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	Microtubule Cytoskeleton Organization Cytoskeleton Organization Cytoskeleton Microtubule-based Process Centrosome Dynein Light Intermediate Chain Binding Cytoplasm Organelle Organization FHF Complex Microtubule Mitotic Spindle Assembly Protein Localization To Perinuclear Region Of Cytoplasm Microtubule Binding Thioesterase Binding Golgi Cis Cisterna Spindle Organization Cytoplasmic Microtubule Organization Regulation Of Microtubule Cytoskeleton Organization Vesicle-mediated Transport HOPS Complex Supramolecular Fiber Organization Cellular Component Assembly Regulation Of Cytoskeleton Organization Cytoskeleton-dependent Intracellular Transport Microtubule Organizing Center Organization Positive Regulation Of Protein Modification Process Mitotic Spindle Organization Spindle Assembly Microtubule Organizing Center Early Endosome To Late Endosome Transport Negative Regulation Of Autophagy Golgi Organization Microtubule Nucleation Intracellular Transport Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Organelle Organization Tumor Necrosis Factor Receptor Binding TORC2 Complex Disassembly Regulation Of Microtubule-based Process Cilium Assembly Meiotic Gene Conversion Primary Ureteric Bud Growth Anterior Visceral Endoderm Cell Migration Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Polarized Secretion Of Basement Membrane Proteins In Epithelium Cell Trailing Edge Membraneless Organelle Assembly Golgi Vesicle Transport Microtubule Cytoskeleton Organization Involved In Mitosis