LY6D and ABCB11

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LY6D	ABCB11
Gene Name		lymphocyte antigen 6 complex, locus D	ATP-binding cassette, sub-family B (MDR/TAP), member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Anchored Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Apical Part Of Cell Intercellular Canaliculus Extracellular Vesicular Exosome
	Molecular Function		Transporter Activity ATP Binding Sodium-exporting ATPase Activity, Phosphorylative Mechanism Canalicular Bile Acid Transmembrane Transporter Activity Bile Acid-exporting ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Cell Adhesion Lymphocyte Differentiation Response To Stilbenoid	Bile Acid Biosynthetic Process Transport Bile Acid Metabolic Process Bile Acid And Bile Salt Transport Canalicular Bile Acid Transport Sodium Ion Transmembrane Transport Small Molecule Metabolic Process Transmembrane Transport
Pathways			Bile acid and bile salt metabolism Metabolism of lipids and lipoproteins Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Recycling of bile acids and salts Synthesis of bile acids and bile salts
Drugs			Adenosine triphosphate Glyburide
Diseases
GWAS			Fasting plasma glucose ( 18521185) Glycated hemoglobin levels ( 20858683) Liver enzyme levels (alkaline phosphatase) ( 22001757) Metabolic syndrome (bivariate traits) ( 21386085) Metabolic traits ( 19060910) Metabolite levels ( 21909109)
Protein-Protein Interactions		3 interactors: ABCB11 ARFIP2 PKIB	3 interactors: HAX1 LY6D NR4A1
Entrez ID		8581	8647
HPRD ID		09370	04436
Ensembl ID		ENSG00000167656	ENSG00000073734
Uniprot IDs		Q14210	O95342
PDB IDs
Enriched GO Terms of Interacting Partners?		Canalicular Bile Acid Transport Negative Regulation Of CAMP-dependent Protein Kinase Activity Bile Acid Secretion Regulation Of CAMP-dependent Protein Kinase Activity
Tagcloud ?			1b1 3a4 abcc2 abcg2 ambrisentan bosentan calcein cyp2c19 cyp3a4 desmethyl endothelin fluorescein geometric gp hek hydroxy hydroxylated hydroxymethyl ls180 mdr1 oatp oatp1b1 oatp1b3 p450 perpetrators pharmacokinetic pregnane transporting
Tagcloud (Difference) ?			1b1 3a4 abcc2 abcg2 ambrisentan bosentan calcein cyp2c19 cyp3a4 desmethyl endothelin fluorescein geometric gp hek hydroxy hydroxylated hydroxymethyl ls180 mdr1 oatp oatp1b1 oatp1b3 p450 perpetrators pharmacokinetic pregnane transporting
Tagcloud (Intersection) ?