LY6D and PKIB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		LY6D	PKIB
Description		lymphocyte antigen 6 family member D	cAMP-dependent protein kinase inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Cell Surface Membrane Side Of Membrane	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Cell Adhesion Lymphocyte Differentiation Response To Stilbenoid	Positive Regulation Of Telomere Maintenance
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		7 interacting genes: ABCB11 AQP6 ARFIP2 ELOVL4 PKIB TMEM31 TMEM86B	9 interacting genes: DYNLL1 E2F1 E2F3 KRTAP3-1 LY6D NLGN3 PIN1 PRKACA PRKACB
Entrez ID		8581	5570
HPRD ID		09370	06075
Ensembl ID		ENSG00000167656	ENSG00000135549
Uniprot IDs		Q14210	Q9C010
PDB IDs
Enriched GO Terms of Interacting Partners?		PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Nitrate Transmembrane Transport Canalicular Bile Acid Transmembrane Transporter Activity Positive Regulation Of Bile Acid Secretion Canalicular Bile Acid Transport D-lysine 5,6-aminomutase Activity Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Intracellular Canaliculus Regulation Of Bile Acid Secretion ABC-type Bile Acid Transporter Activity Membrane Curvature Sensor Activity Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Intercellular Canaliculus Monoatomic Anion Channel Activity Renal Water Transport Fatty Acid Elongation, Saturated Fatty Acid Ammonium Transmembrane Transport Ammonium Channel Activity CAMP-dependent Protein Kinase Inhibitor Activity Carboxylic Acid Biosynthetic Process G Protein-coupled Photoreceptor Activity Bile Acid Transmembrane Transporter Activity Regulation Of Bile Acid Metabolic Process Water Channel Activity Carbon Dioxide Transport Very Long-chain Fatty Acid Biosynthetic Process Fatty Acid Elongation Fatty Acid Metabolic Process Xenobiotic Export From Cell ABC-type Xenobiotic Transporter Activity Xenobiotic Transmembrane Transport Phosphatidylcholine Acyl-chain Remodeling Phospholipid Homeostasis Regulation Of Fatty Acid Beta-oxidation Protein Localization To Phagophore Assembly Site Lipid Metabolic Process Long-chain Fatty-acyl-CoA Biosynthetic Process Bile Acid And Bile Salt Transport GTP-dependent Protein Binding Ether Lipid Metabolic Process	Negative Regulation Of Fat Cell Proliferation CAMP-dependent Protein Kinase Complex CAMP-dependent Protein Kinase Activity High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Vascular Endothelial Cell Response To Fluid Shear Stress Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis DNA-binding Transcription Activator Activity Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Multicellular Organismal-level Water Homeostasis Cellular Response To Fluid Shear Stress Negative Regulation Of Smoothened Signaling Pathway Centrosome Ciliary Base Response To Fluid Shear Stress Regulation Of Protein Processing Regulation Of Protein Maturation Cis-trans Isomerase Activity Negative Regulation Of TORC1 Signaling TORC1 Signaling Cellular Response To Stress Multicellular Organismal-level Chemical Homeostasis Scaffold Protein Binding Regulation Of Biological Quality Negative Regulation Of Catabolic Process Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Smoothened Signaling Pathway TOR Signaling Positive Regulation Of Insulin Secretion Neural Tube Closure Negative Regulation Of TOR Signaling Tube Closure Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Regulation Of TORC1 Signaling Protein Peptidyl-prolyl Isomerization Phosphothreonine Residue Binding Positive Regulation Of Peptide Hormone Secretion Positive Regulation Of Peptide Secretion Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Rhythmic Synaptic Transmission Symmetric, GABA-ergic, Inhibitory Synapse Renal System Process Lens Fiber Cell Apoptotic Process RNA Polymerase II Transcription Regulator Complex Tube Formation
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